1-(3-amino-1,2-benzoxazol-5-yl)-6-{2-fluoro-4-[2-(pyrrolidin-1-ylmethyl)phenyl]phenyl}-3-(trifluoromethyl)-1H,4H,5H,6H,7H-pyrazolo[3,4-c]pyridin-7-one

• 常用名: 1-(3-amino-1,2-benzoxazol-5-yl)-6-{2-fluoro-4-[2-(pyrrolidin-1-ylmethyl)phenyl]phenyl}-3-(trifluoromethyl)-1H,4H,5H,6H,7H-pyrazolo[3,4-c]pyridin-7-one
• 英文名: 1-(3-amino-1,2-benzoxazol-5-yl)-6-{2-fluoro-4-[2-(pyrrolidin-1-ylmethyl)phenyl]phenyl}-3-(trifluoromethyl)-1H,4H,5H,6H,7H-pyrazolo[3,4-c]pyridin-7-one
• CAS号: 280118-31-2
• 分子量: 590.6
• 密度: N/A
• 沸点: N/A
• 分子式: C₃₁H₂₆F₄N₆O₂
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: 1-(3-amino-1,2-benzoxazol-5-yl)-6-{2-fluoro-4-[2-(pyrrolidin-1-ylmethyl)phenyl]phenyl}-3-(trifluoromethyl)-1H,4H,5H,6H,7H-pyrazolo[3,4-c]pyridin-7-one

物理化学性质

• 分子式: C₃₁H₂₆F₄N₆O₂
• 分子量: 590.6
• InChIKey: KVMNDDXISQYKQH-UHFFFAOYSA-N
• SMILES: C1CCN(C1)CC2=CC=CC=C2C3=CC(=C(C=C3)N4CCC5=C(C4=O)N(N=C5C(F)(F)F)C6=CC7=C(C=C6)ON=C7N)F

靶点实验

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实验名称：Volume of distribution in dog 来源：ChEMBL 靶标：Canis lupus familiaris External Id：CHEMBL869240

实验名称：Half life in orally dosed dog 来源：ChEMBL 靶标：Canis lupus familiaris External Id：CHEMBL869241

实验名称：Oral bioavailability in orally dosed dog 来源：ChEMBL 靶标：Canis lupus familiaris External Id：CHEMBL869242

实验名称：Antithrombotic activity in rabbit arterio-venous shunt thrombosis model 来源：ChEMBL 靶标：Oryctolagus cuniculus External Id：CHEMBL869244

实验名称：Anticoagulant activity in plasma by PT assay 来源：ChEMBL 靶标：Tissue factor External Id：CHEMBL868638

实验名称：Protein binding in plasma by equilibrium dialysis assay 来源：ChEMBL 靶标：N/A External Id：CHEMBL869833

实验名称：Apparent permeability in Caco-2 cells 来源：ChEMBL 靶标：Caco-2 External Id：CHEMBL868640

实验名称：Clearance in dog 来源：ChEMBL 靶标：Canis lupus familiaris External Id：CHEMBL869239

实验名称：Binding affinity to human F10a 来源：ChEMBL 靶标：Coagulation factor X External Id：CHEMBL868637

实验名称：Enzyme Assay and Determination of the Inhibition Constants. from Article 10.1016/j.bm... 来源：BindingDB 靶标：N/A External Id：BindingDB_1620_1

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