2-(2,6-Dioxopiperidin-3-yl)-3-oxoisoindoline-5-sulfonyl fluoride

• 常用名: 2-(2,6-Dioxopiperidin-3-yl)-3-oxoisoindoline-5-sulfonyl fluoride
• 英文名: 2-(2,6-Dioxopiperidin-3-yl)-3-oxoisoindoline-5-sulfonyl fluoride
• CAS号: 2803819-61-4
• 分子量: 326.30
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₃H₁₁FN₂O₅S
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: 2-(2,6-Dioxopiperidin-3-yl)-3-oxoisoindoline-5-sulfonyl fluoride

物理化学性质

• 分子式: C₁₃H₁₁FN₂O₅S
• 分子量: 326.30
• InChIKey: IAJNULNMWPZFDR-UHFFFAOYSA-N
• SMILES: O=C1CCC(N2Cc3ccc(S(=O)(=O)F)cc3C2=O)C(=O)N1

靶点实验

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实验名称：Inhibition of CRBN (unknown origin) 来源：ChEMBL 靶标：Protein cereblon External Id：CHEMBL5515863

实验名称：Stability of the compound in human plasma assessed as half life 来源：ChEMBL 靶标：N/A External Id：CHEMBL5515862

实验名称：Binding affinity to human StrepTag-Avi-CRBN-His6-Spy-fused DDB1deltaB mutant complex ... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5375580

实验名称：Stability of the compound in human plasma assessed as half life at 1 uM by LC-MS/MS a... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5375576

实验名称：Metabolic stability in human plasma assessed as half life and measured upto 240 mins ... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5225190

实验名称：Displacement of BODIPY-lenalidomide from human N-terminal NanoLuc-fused CRBN expresse... 来源：ChEMBL 靶标：Protein cereblon External Id：CHEMBL5375575

实验名称：Metabolic stability in human hepatocytes assessed as intrinsic clearance and measured... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5225192

实验名称：Microsomal stability in human liver microsomes assessed as intrinsic clearance and me... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5225191

实验名称：Inhibition of N-terminal fused Nano Luc CRBN in HEK293T cells by NanoBRET CRBN engage... 来源：ChEMBL 靶标：Protein cereblon External Id：CHEMBL5380587

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