PROTAC SOS1 degrader-5

• 常用名: PROTAC SOS1 degrader-5
• 英文名: PROTAC SOS1 degrader-5
• CAS号: 2836273-61-9
• 分子量: 872.9
• 密度: N/A
• 沸点: N/A
• 分子式: C₄₅H₅₁F₃N₈O₇
• 熔点: N/A
• 闪点: N/A

PROTAC SOS1 degrader-5名称

• 英文名: PROTAC SOS1 degrader-5

PROTAC SOS1 degrader-5物理化学性质

• 分子式: C₄₅H₅₁F₃N₈O₇
• 分子量: 872.9
• InChIKey: WLWKNXUSLSOAGM-HSGLFRJESA-N
• SMILES: CC1=NC2=CC(=C(C=C2C(=N1)N[C@H](C)C3=CC(=CC(=C3)N)C(F)(F)F)OCC4(CC4)CN(C)C(=O)CCCCCCNC5=CC=CC6=C5C(=O)N(C6=O)C7CCC(=O)NC7=O)OC

PROTAC SOS1 degrader-5靶点实验

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实验名称：Antiproliferative activity against human NCI-H358 cells assessed as inhibition of cel... 来源：ChEMBL 靶标：NCI-H358 External Id：CHEMBL5540288

实验名称：PROTAC activity at CRBN/SOS1 in human NCI-H358 cells assessed as induction of SOS1 de... 来源：ChEMBL 靶标：Protein cereblon External Id：CHEMBL5540289

实验名称：PROTAC activity at CRBN/SOS1 in human NCI-H358 cells assessed as induction of SOS1 de... 来源：ChEMBL 靶标：Protein cereblon External Id：CHEMBL5540290

实验名称：Potency index, ratio of test compound IC50 to BI3406 IC50 for antiproliferative activ... 来源：ChEMBL 靶标：NCI-H358 External Id：CHEMBL5540291

实验名称：PROTAC activity at CRBN/SOS1 in human NCI-H358 cells assessed as induction of SOS1 de... 来源：ChEMBL 靶标：Protein cereblon External Id：CHEMBL5540292

实验名称：PROTAC activity at CRBN/SOS1 in human NCI-H358 cells assessed as induction of SOS1 de... 来源：ChEMBL 靶标：Protein cereblon External Id：CHEMBL5540293

实验名称：Tmax in BALB/c nude mouse at 10 mg/kg, ip measured upto 24 hrs by LC-MS/MS analysis 来源：ChEMBL 靶标：N/A External Id：CHEMBL5540298

实验名称：AUC (0 to t) in BALB/c nude mouse at 10 mg/kg, ip measured upto 24 hrs by LC-MS/MS an... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5540299

实验名称：Cmax in BALB/c nude mouse at 10 mg/kg, ip measured upto 24 hrs by LC-MS/MS analysis 来源：ChEMBL 靶标：N/A External Id：CHEMBL5540300

实验名称：AUC (0 to infinity) in BALB/c nude mouse at 10 mg/kg, ip measured upto 24 hrs by LC-M... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5540301

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