紫草酸

• 常用名: 紫草酸
• 英文名: Lithospermic acid
• CAS号: 28831-65-4
• 分子量: 538.456
• 密度: 1.6±0.1 g/cm3
• 沸点: 862.6±65.0 °C at 760 mmHg
• 分子式: C₂₇H₂₂O₁₂
• 熔点: N/A
• 闪点: 291.3±27.8 °C

紫草酸用途

Lithospermic acid ((+)-Lithospermic acid) 是从丹参中分离出的一种植物来源的多环酚类羧酸,对 CCl4 诱导的急性和体外肝损伤具有抗氧化和保肝活性。

紫草酸名称

• 中文名: 紫草酸
• 英文名: (2S,3S)-4-[(E)-3-[(1R)-1-carboxy-2-(3,4-dihydroxyphenyl)ethoxy]-3-oxoprop-1-enyl]-2-(3,4-dihydroxyphenyl)-7-hydroxy-2,3-dihydro-1-benzofuran-3-carboxylic acid

紫草酸生物活性

• 描述: Lithospermic acid ((+)-Lithospermic acid) 是从丹参中分离出的一种植物来源的多环酚类羧酸,对 CCl4 诱导的急性和体外肝损伤具有抗氧化和保肝活性。
• 相关类别:
  研究领域 >> 其他
  信号通路 >> 其他 >> 其他
• 参考文献:

  [1]. Chan KW, et al. Anti-oxidative and hepatoprotective effects of lithospermic acid against carbon tetrachloride-induced liver oxidative damage in vitro and in vivo. Oncol Rep. 2015 Aug;34(2):673-80.

紫草酸物理化学性质

• 密度: 1.6±0.1 g/cm3
• 沸点: 862.6±65.0 °C at 760 mmHg
• 分子式: C₂₇H₂₂O₁₂
• 分子量: 538.456
• 闪点: 291.3±27.8 °C
• 精确质量: 538.111145
• PSA: 211.28000
• LogP: 1.45
• InChIKey: UJZQBMQZMKFSRV-RGKBJLTCSA-N
• SMILES: O=C(C=Cc1ccc(O)c2c1C(C(=O)O)C(c1ccc(O)c(O)c1)O2)OC(Cc1ccc(O)c(O)c1)C(=O)O
• 蒸汽压: 0.0±0.3 mmHg at 25°C
• 折射率: 1.745
• 储存条件: 2-8C

紫草酸靶点实验

查看更多实验

实验名称：HepG2 viability counterscreen (readout 2: ATP content) against the NCATS DSHEA and TC... 来源：NCGC 靶标：N/A External Id：DSHEA-v1-HepG2-viability-CTG-ATP

实验名称：HIV Enzyme Data 来源：NIAID 靶标：N/A External Id：HIV Enzyme Data

实验名称：Cytotoxicity against human HaCaT cells at 50 to 200 ug/mL by MTT assay 来源：ChEMBL 靶标：HaCaT External Id：CHEMBL993544

实验名称：HIV Cellular Data 来源：NIAID 靶标：N/A External Id：HIV Cellular Data

实验名称：Increase in serine palmitoyltransferase 1 mRNA expression in human HaCaT cells by RT-... 来源：ChEMBL 靶标：HaCaT External Id：CHEMBL993545

实验名称：Primary qHTS for inhibitors of NSP2Pro chikungunya virus (CHIKV) 来源：NCGC External Id：APP-Toga-CHIKV-nsp2-p

实验名称：Inhibition of human recombinant carbonic anhydrase 1 preincubated for 15 mins at room... 来源：ChEMBL 靶标：Carbonic anhydrase 1 External Id：CHEMBL3631188

实验名称：Inhibition of human recombinant carbonic anhydrase 12 preincubated for 15 mins at roo... 来源：ChEMBL 靶标：Carbonic anhydrase 12 External Id：CHEMBL3631192

实验名称：Inhibition of human recombinant carbonic anhydrase 7 preincubated for 15 mins at room... 来源：ChEMBL 靶标：Carbonic anhydrase 7 External Id：CHEMBL3631191

实验名称：Inhibition of human recombinant carbonic anhydrase 4 preincubated for 15 mins at room... 来源：ChEMBL 靶标：Carbonic anhydrase 4 External Id：CHEMBL3631190

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紫草酸英文别名

• 4-{(E)-2-[1-Carboxy-2-(3,4-dihydroxy-phenyl)-ethoxycarbonyl]-vinyl}-2-(3,4-dihydroxy-phenyl)-7-hydroxy-2,3-dihydro-benzofuran-3-carboxylic acid
• 4-{(1E)-3-[1-Carboxy-2-(3,4-dihydroxyphenyl)ethoxy]-3-oxo-1-propen-1-yl}-2-(3,4-dihydroxyphenyl)-7-hydroxy-2,3-dihydro-1-benzofuran-3-carboxylic acid
• (2S,3S)-4-{(1E)-3-[(1R)-1-Carboxy-2-(3,4-dihydroxyphenyl)ethoxy]-3-oxo-1-propen-1-yl}-2-(3,4-dihydroxyphenyl)-7-hydroxy-2,3-dihydro-1-benzofuran-3-carboxylic acid
• Lithospermic acid
• Lithospermsaeure
• (2S,3S)-4-{(1E)-3-[(1R)-1-Carboxy-2-(3,4-dihydroxyphenyl)ethoxy]-3-oxoprop-1-en-1-yl}-2-(3,4-dihydroxyphenyl)-7-hydroxy-2,3-dihydro-1-benzofuran-3-carboxylic acid