(2R)-2-amino-N-[[5-(6-methyl-2-pyridinyl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]methyl]-3-phenylpropanamide

• 常用名: (2R)-2-amino-N-[[5-(6-methyl-2-pyridinyl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]methyl]-3-phenylpropanamide
• 英文名: (2R)-2-amino-N-[[5-(6-methyl-2-pyridinyl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]methyl]-3-phenylpropanamide
• CAS号: 2883580-95-6
• 分子量: 452.5
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₅H₂₄N₈O
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: (2R)-2-amino-N-[[5-(6-methyl-2-pyridinyl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]methyl]-3-phenylpropanamide

物理化学性质

• 分子式: C₂₅H₂₄N₈O
• 分子量: 452.5
• InChIKey: GIXYMNJSHSCLBB-LJQANCHMSA-N
• SMILES: CC1=NC(=CC=C1)C2=C(N=C(N2)CNC(=O)[C@@H](CC3=CC=CC=C3)N)C4=CN5C(=NC=N5)C=C4

靶点实验

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实验名称：Clearance in male Sprague-Dawley rat at 15 mg/kg, po measured after 8 hrs by UPLC-MS/... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5500979

实验名称：Cmax in male Sprague-Dawley rat at 15 mg/kg, po measured after 8 hrs by UPLC-MS/MS an... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5500978

实验名称：Tmax in male Sprague-Dawley rat at 15 mg/kg, po measured after 8 hrs by UPLC-MS/MS an... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5500977

实验名称：Half-life in male Sprague-Dawley rat at 15 mg/kg, po measured after 8 hrs by UPLC-MS/... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5500976

实验名称：MRT (0 to t) in male Sprague-Dawley rat at 15 mg/kg, po measured after 8 hrs by UPLC-... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5500975

实验名称：AUC (0 to infinity) in male Sprague-Dawley rat at 15 mg/kg, po measured after 8 hrs b... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5500974

实验名称：AUC (0 to t) in male Sprague-Dawley rat at 15 mg/kg, po measured after 8 hrs by UPLC-... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5500973

实验名称：Oral bioavailability in male Sprague-Dawley rat at 15 mg/kg measured after 8 hrs by U... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5500972

实验名称：Clearance in male Sprague-Dawley rat at 4 mg/kg, iv measured after 8 hrs by UPLC-MS/M... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5500971

实验名称：Cmax in male Sprague-Dawley rat at 4 mg/kg, iv measured after 8 hrs by UPLC-MS/MS ana... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5500970

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