3-[2-[[(3S)-1-(cyclopropanecarbonyl)piperidin-3-yl]amino]pyrimidin-4-yl]-2-(3,4-dichlorophenyl)-5,6-dihydro-4H-cyclopenta[d]imidazole-5-carboxamide

• 常用名: 3-[2-[[(3S)-1-(cyclopropanecarbonyl)piperidin-3-yl]amino]pyrimidin-4-yl]-2-(3,4-dichlorophenyl)-5,6-dihydro-4H-cyclopenta[d]imidazole-5-carboxamide
• 英文名: 3-[2-[[(3S)-1-(cyclopropanecarbonyl)piperidin-3-yl]amino]pyrimidin-4-yl]-2-(3,4-dichlorophenyl)-5,6-dihydro-4H-cyclopenta[d]imidazole-5-carboxamide
• CAS号: 2911640-63-4
• 分子量: 540.4
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₆H₂₇Cl₂N₇O₂
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: 3-[2-[[(3S)-1-(cyclopropanecarbonyl)piperidin-3-yl]amino]pyrimidin-4-yl]-2-(3,4-dichlorophenyl)-5,6-dihydro-4H-cyclopenta[d]imidazole-5-carboxamide

物理化学性质

• 分子式: C₂₆H₂₇Cl₂N₇O₂
• 分子量: 540.4
• InChIKey: MKHLHLAXBRMALM-DJNXLDHESA-N
• SMILES: NC(=O)C1Cc2nc(-c3ccc(Cl)c(Cl)c3)n(-c3ccnc(NC4CCCN(C(=O)C5CC5)C4)n3)c2C1

靶点实验

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实验名称：Inhibition of JNK3 in primary rat cortex neuron cells assessed as reduction in Abeta1... 来源：ChEMBL 靶标：Mitogen-activated protein kinase 10 External Id：CHEMBL5386803

实验名称：Inhibition of JNK3 in primary rat cortex neuron cells assessed as reduction in Abeta1... 来源：ChEMBL 靶标：Mitogen-activated protein kinase 10 External Id：CHEMBL5386802

实验名称：Neuroprotective activity against Abeta42-induced neuronal apoptosis in Sprague-Dawley... 来源：ChEMBL 靶标：Cortical neurone External Id：CHEMBL5386800

实验名称：Selectivity ratio of IC50 for inhibition of JNK2 (unknown origin) to IC50 for inhibit... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5386799

实验名称：Selectivity ratio of IC50 for inhibition of p38alpha (unknown origin) to IC50 for inh... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5386798

实验名称：Selectivity ratio of IC50 for inhibition of GSK3beta (unknown origin) to IC50 for inh... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5386797

实验名称：Selectivity ratio of IC50 for inhibition of JNK1 (unknown origin) to IC50 for inhibit... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5386796

实验名称：Inhibition of p38alpha (unknown origin) at 1 uM relative to control 来源：ChEMBL 靶标：Mitogen-activated protein kinase 14 External Id：CHEMBL5386795

实验名称：Inhibition of JNK2 (unknown origin) at 1 uM relative to control 来源：ChEMBL 靶标：Mitogen-activated protein kinase 9 External Id：CHEMBL5386794

实验名称：Inhibition of JNK1 (unknown origin) at 1 uM relative to control 来源：ChEMBL 靶标：Mitogen-activated protein kinase 8 External Id：CHEMBL5386793

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