(2S,3R)-N-(3-chloro-4-fluorophenyl)-1-(3-cyano-6-methyl-4-(trifluoromethyl)pyridin-2-yl)-3-(hydroxymethyl)-N-(methyl-d3)azetidine-2-carboxamide

• 常用名: (2S,3R)-N-(3-chloro-4-fluorophenyl)-1-(3-cyano-6-methyl-4-(trifluoromethyl)pyridin-2-yl)-3-(hydroxymethyl)-N-(methyl-d3)azetidine-2-carboxamide
• 英文名: (2S,3R)-N-(3-chloro-4-fluorophenyl)-1-(3-cyano-6-methyl-4-(trifluoromethyl)pyridin-2-yl)-3-(hydroxymethyl)-N-(methyl-d3)azetidine-2-carboxamide
• CAS号: 2923508-77-2
• 分子量: 459.8
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₀H₁₇ClF₄N₄O₂
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: (2S,3R)-N-(3-chloro-4-fluorophenyl)-1-(3-cyano-6-methyl-4-(trifluoromethyl)pyridin-2-yl)-3-(hydroxymethyl)-N-(methyl-d3)azetidine-2-carboxamide

物理化学性质

• 分子式: C₂₀H₁₇ClF₄N₄O₂
• 分子量: 459.8
• InChIKey: PBBZMQSTYBBLDS-PXBRQSFWSA-N
• SMILES: [2H]C([2H])([2H])N(C1=CC(=C(C=C1)F)Cl)C(=O)[C@@H]2[C@@H](CN2C3=NC(=CC(=C3C#N)C(F)(F)F)C)CO

靶点实验

查看更多实验

实验名称：Plasma protein binding in mouse assessed as unbound fraction 来源：ChEMBL 靶标：N/A External Id：CHEMBL5550719

实验名称：Intrinsic clearance in human liver microsomes at 1 uM preincubated for 10 mins follow... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5550720

实验名称：Clearance in human liver microsomes at 1 uM preincubated for 10 mins followed by NADP... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5550721

实验名称：Intrinsic clearance in mouse liver microsomes at 1 uM preincubated for 10 mins follow... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5550722

实验名称：Clearance in mouse liver microsomes at 1 uM preincubated for 10 mins followed by NADP... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5550723

实验名称：Half life in human plasma incubated for 50 mins by LC-MS/MS analysis 来源：ChEMBL 靶标：N/A External Id：CHEMBL5550729

实验名称：Half life in mouse plasma incubated for 50 mins by LC-MS/MS analysis 来源：ChEMBL 靶标：N/A External Id：CHEMBL5550730

实验名称：Clearance in CD-1 mouse at 1 mg/kg,iv measured upto 24 hrs 来源：ChEMBL 靶标：N/A External Id：CHEMBL5550731

实验名称：Volume of distribution at steady state in CD-1 mouse at 10 mg/kg,po measured upto 24 ... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5550732

实验名称：MRT (0 to t) in CD-1 mouse at 10 mg/kg,po measured upto 24 hrs 来源：ChEMBL 靶标：N/A External Id：CHEMBL5550733

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