N-(2-Chloro-6-methylphenyl)-2-((2,6-dimethyl-4-pyrimidinyl)amino)-5-thiazolecarboxamide

• 常用名: N-(2-Chloro-6-methylphenyl)-2-((2,6-dimethyl-4-pyrimidinyl)amino)-5-thiazolecarboxamide
• 英文名: N-(2-Chloro-6-methylphenyl)-2-((2,6-dimethyl-4-pyrimidinyl)amino)-5-thiazolecarboxamide
• CAS号: 302961-18-8
• 分子量: 373.9
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₇H₁₆ClN₅OS
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: N-(2-Chloro-6-methylphenyl)-2-((2,6-dimethyl-4-pyrimidinyl)amino)-5-thiazolecarboxamide

物理化学性质

• 分子式: C₁₇H₁₆ClN₅OS
• 分子量: 373.9
• InChIKey: WFRLFWGASBLYTC-UHFFFAOYSA-N
• SMILES: Cc1cc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)nc(C)n1

靶点实验

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实验名称：Human LCK proto-oncogene, Src family tyrosine kinase (Src family) 来源：IUPHAR-DB 靶标：LCK proto-oncogene, Src family tyrosine kinase (Src family) [Homo sapiens] External Id：2053_Human

实验名称：In vitro inhibitory activity against recombinant p56 lck tyrosine kinase expressed as... 来源：ChEMBL 靶标：N/A External Id：CHEMBL829926

实验名称：Human HCK proto-oncogene, Src family tyrosine kinase (Src family) 来源：IUPHAR-DB 靶标：HCK proto-oncogene, Src family tyrosine kinase (Src family) [Homo sapiens] External Id：2032_Human

实验名称：Half-life was determined in rats at a single dose of 10 mg/kg i.v. and p.o. 来源：ChEMBL 靶标：N/A External Id：CHEMBL839325

实验名称：Human Janus kinase 3 (Janus kinase (JakA) family) 来源：IUPHAR-DB 靶标：Janus kinase 3 (Janus kinase (JakA) family) [Homo sapiens] External Id：2049_Human

实验名称：Human BLK proto-oncogene, Src family tyrosine kinase (Src family) 来源：IUPHAR-DB 靶标：BLK proto-oncogene, Src family tyrosine kinase (Src family) [Homo sapiens] External Id：1940_Human

实验名称：Antiproliferative activity against human K562 cells after 72 hrs 来源：ChEMBL 靶标：K562 External Id：CHEMBL914486

实验名称：Human FYN proto-oncogene, Src family tyrosine kinase (Src family) 来源：IUPHAR-DB 靶标：FYN proto-oncogene, Src family tyrosine kinase (Src family) [Homo sapiens] External Id：2026_Human

实验名称：Antiproliferative activity against human PC3 cells after 72 hrs 来源：ChEMBL 靶标：PC-3 External Id：CHEMBL914487

实验名称：Plasma protein binding in mouse was determined 来源：ChEMBL 靶标：N/A External Id：CHEMBL835965

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