4-(3-chloro-2-fluorophenoxy)-N-[2-[2-[2-[[2-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]oxyacetyl]amino]ethoxy]ethoxy]ethyl]-1-[[6-(1,3-thiazol-2-ylamino)-2-pyridinyl]methyl]cyclohexane-1-carboxamide

• 常用名: 4-(3-chloro-2-fluorophenoxy)-N-[2-[2-[2-[[2-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]oxyacetyl]amino]ethoxy]ethoxy]ethyl]-1-[[6-(1,3-thiazol-2-ylamino)-2-pyridinyl]methyl]cyclohexane-1-carboxamide
• 英文名: 4-(3-chloro-2-fluorophenoxy)-N-[2-[2-[2-[[2-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]oxyacetyl]amino]ethoxy]ethoxy]ethyl]-1-[[6-(1,3-thiazol-2-ylamino)-2-pyridinyl]methyl]cyclohexane-1-carboxamide
• CAS号: 3038446-90-8
• 分子量: 906.4
• 密度: N/A
• 沸点: N/A
• 分子式: C₄₃H₄₅ClFN₇O₁₀S
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: 4-(3-chloro-2-fluorophenoxy)-N-[2-[2-[2-[[2-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]oxyacetyl]amino]ethoxy]ethoxy]ethyl]-1-[[6-(1,3-thiazol-2-ylamino)-2-pyridinyl]methyl]cyclohexane-1-carboxamide

物理化学性质

• 分子式: C₄₃H₄₅ClFN₇O₁₀S
• 分子量: 906.4
• InChIKey: LAZHTWDJEQSMOY-UHFFFAOYSA-N
• SMILES: C1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C(=CC=C3)OCC(=O)NCCOCCOCCNC(=O)C4(CCC(CC4)OC5=C(C(=CC=C5)Cl)F)CC6=NC(=CC=C6)NC7=NC=CS7

靶点实验

查看更多实验

实验名称：Antiproliferative activity against human NGP cells assessed as reduction in cell viab... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5333215

实验名称：PROTAC activity at AURKA/CRBN in human NGP cells assessed as AURKA degradation measur... 来源：ChEMBL 靶标：Aurora kinase A External Id：CHEMBL5333198

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