Ihmt-idh1-053

• 常用名: Ihmt-idh1-053
• 英文名: Ihmt-idh1-053
• CAS号: 3049485-80-2
• 分子量: 532.6
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₅H₃₃FN₆O₄S
• 熔点: N/A
• 闪点: N/A

Ihmt-idh1-053名称

• 英文名: Ihmt-idh1-053

Ihmt-idh1-053物理化学性质

• 分子式: C₂₅H₃₃FN₆O₄S
• 分子量: 532.6
• InChIKey: ZUPHYBXQUOQKRE-HTAPYJJXSA-N
• SMILES: C[C@@H](C1=CC=C(C=C1)N2CCC(CC2)NS(=O)(=O)C=C)NC3=NC=C(C(=N3)N4[C@H](COC4=O)C(C)C)F

Ihmt-idh1-053靶点实验

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实验名称：Tmax in Sprague-Dawley rat at 1 mg/kg, iv measured upto 24 hrs by LC-MS/MS analysis 来源：ChEMBL 靶标：N/A External Id：CHEMBL5371986

实验名称：Antiproliferative activity against human primary AML cells expressing IDH1-R132 mutan... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5371984

实验名称：Half life in Sprague-Dawley rat at 1 mg/kg, iv measured upto 24 hrs by LC-MS/MS analy... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5371985

实验名称：Antiproliferative activity against human HT-1080 cells assessed as cell viability at ... 来源：ChEMBL 靶标：HT-1080 External Id：CHEMBL5371983

实验名称：Binding affinity to IDH1 R132H mutant (unknown origin) expressed in Escherichia coli ... 来源：ChEMBL 靶标：Isocitrate dehydrogenase [NADP] cytoplasmic External Id：CHEMBL5371976

实验名称：Binding affinity to IDH1 R132H mutant (unknown origin) expressed in Escherichia coli ... 来源：ChEMBL 靶标：Isocitrate dehydrogenase [NADP] cytoplasmic External Id：CHEMBL5371977

实验名称：Inhibition of IDH1 R132H mutant (unknown origin) expressed in HEK293T cells assessed ... 来源：ChEMBL 靶标：Isocitrate dehydrogenase [NADP] cytoplasmic External Id：CHEMBL5371974

实验名称：Inhibition of IDH1 R132H mutant (unknown origin) expressed in Escherichia coli BL21 (... 来源：ChEMBL 靶标：Isocitrate dehydrogenase [NADP] cytoplasmic External Id：CHEMBL5371973

实验名称：In vivo inhibition of IDH1 mutant activity in tumor of human HT-1080 cells xenografte... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5371998

实验名称：Clearance in Sprague-Dawley rat at 10 mg/kg, po measured upto 24 hrs by LC-MS/MS anal... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5371996

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