3-cyclopropyl-4-[4-(difluoromethoxy)phenyl]-6-(2-methylindazol-5-yl)-2H-pyrazolo[4,3-b]pyridin-5-one

• 常用名: 3-cyclopropyl-4-[4-(difluoromethoxy)phenyl]-6-(2-methylindazol-5-yl)-2H-pyrazolo[4,3-b]pyridin-5-one
• 英文名: 3-cyclopropyl-4-[4-(difluoromethoxy)phenyl]-6-(2-methylindazol-5-yl)-2H-pyrazolo[4,3-b]pyridin-5-one
• CAS号: 3056570-19-2
• 分子量: 447.4
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₄H₁₉F₂N₅O₂
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: 3-cyclopropyl-4-[4-(difluoromethoxy)phenyl]-6-(2-methylindazol-5-yl)-2H-pyrazolo[4,3-b]pyridin-5-one

物理化学性质

• 分子式: C₂₄H₁₉F₂N₅O₂
• 分子量: 447.4
• InChIKey: QEASMQZYZCGOSA-UHFFFAOYSA-N
• SMILES: CN1C=C2C=C(C=CC2=N1)C3=CC4=NNC(=C4N(C3=O)C5=CC=C(C=C5)OC(F)F)C6CC6

靶点实验

查看更多实验

实验名称：Oral bioavailability in mouse at 1 mg/kg 来源：ChEMBL 靶标：N/A External Id：CHEMBL5521416

实验名称：Half life in mouse at 1 mg/kg, po or 0.5 mg/kg, iv 来源：ChEMBL 靶标：N/A External Id：CHEMBL5521415

实验名称：Volume of distribution at steady state in mouse at 1 mg/kg, po or 0.5 mg/kg, iv 来源：ChEMBL 靶标：N/A External Id：CHEMBL5521414

实验名称：Clearance in mouse at 1 mg/kg, po or 0.5 mg/kg, iv 来源：ChEMBL 靶标：N/A External Id：CHEMBL5521413

实验名称：Intrinsic clearance in mouse hepatocytes measured per 10^6 cells 来源：ChEMBL 靶标：N/A External Id：CHEMBL5521412

实验名称：Time dependent inhibition of CYP2C9 in human liver microsomes 来源：ChEMBL 靶标：Cytochrome P450 2C9 External Id：CHEMBL5521411

实验名称：Time dependent inhibition of CYP2C19 in human liver microsomes 来源：ChEMBL 靶标：Cytochrome P450 2C19 External Id：CHEMBL5521410

实验名称：Time dependent inhibition of CYP2D6 in human liver microsomes 来源：ChEMBL 靶标：Cytochrome P450 2D6 External Id：CHEMBL5521409

实验名称：Time dependent inhibition of CYP1A2 in human liver microsomes 来源：ChEMBL 靶标：Cytochrome P450 1A2 External Id：CHEMBL5521408

实验名称：Time dependent inhibition of CYP3A4 in human liver microsomes 来源：ChEMBL 靶标：Cytochrome P450 3A4 External Id：CHEMBL5521407

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