N-(2,1,3-Benzothiadiazol-4-ylsulfonyl)glycine

• 常用名: N-(2,1,3-Benzothiadiazol-4-ylsulfonyl)glycine
• 英文名: N-(2,1,3-Benzothiadiazol-4-ylsulfonyl)glycine
• CAS号: 312591-21-2
• 分子量: 273.289
• 密度: 1.7±0.1 g/cm3
• 沸点: 524.2±56.0 °C at 760 mmHg
• 分子式: C₈H₇N₃O₄S₂
• 熔点: N/A
• 闪点: 270.8±31.8 °C

用途

N-(2,1,3-苯并噻二唑-4-基磺酰基)甘氨酸是甘氨酸(HY-Y0966)衍生物[1]。

名称

• 英文名: N-(2,1,3-Benzothiadiazol-4-ylsulfonyl)glycine

生物活性

• 描述: N-(2,1,3-苯并噻二唑-4-基磺酰基)甘氨酸是甘氨酸(HY-Y0966)衍生物[1]。
• 相关类别:
  研究领域 >> 其他
  信号通路 >> 其他 >> 其他
• 体外研究: 氨基酸和氨基酸衍生物已被商业化用作能量补充剂。它们影响合成代谢激素的分泌、运动期间的燃料供应、压力相关任务期间的精神表现,并防止运动引起的肌肉损伤。它们被认为是有益的能生膳食物质[1]。
• 参考文献:

  [1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.

物理化学性质

• 密度: 1.7±0.1 g/cm3
• 沸点: 524.2±56.0 °C at 760 mmHg
• 分子式: C₈H₇N₃O₄S₂
• 分子量: 273.289
• 闪点: 270.8±31.8 °C
• 精确质量: 272.987793
• LogP: 0.37
• InChIKey: PCCKBSAJRWIUCS-UHFFFAOYSA-N
• SMILES: O=C(O)CNS(=O)(=O)c1cccc2nsnc12
• 蒸汽压: 0.0±1.4 mmHg at 25°C
• 折射率: 1.687

靶点实验

查看更多实验

实验名称：Primary cell-based high-throughput screening assay for identification of compounds th... 来源：Johns Hopkins Ion Channel Center 靶标：regulator of G-protein signaling 4 isoform 2 [Homo sapiens] External Id：JHICC_RGS_Act_HTS

实验名称：Luminescence-based cell-based primary high throughput screening assay to identify ago... 来源：The Scripps Research Institute Molecular Screening Center 靶标：mu-type opioid receptor isoform MOR-1 [Homo sapiens] External Id：OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN

实验名称：QFRET-based biochemical primary high throughput screening assay to identify exosite i... 来源：The Scripps Research Institute Molecular Screening Center 靶标：disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens] External Id：ADAM17_INH_QFRET_1536_1X%INH PRUN

实验名称：Fluorescence-based cell-based primary high throughput screening assay to identify ago... 来源：The Scripps Research Institute Molecular Screening Center 靶标：muscarinic acetylcholine receptor M1 [Homo sapiens] External Id：CHRM1_AG_FLUO8_1536_1X%ACT PRUN

实验名称：uHTS identification of small molecule activators of the adaptive arm of the Unfolded ... 来源：Burnham Center for Chemical Genomics 靶标：N/A External Id：BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay

实验名称：High throughput fluorescence intensity-based biochemical assay to screen for small mo... 来源：University of Pittsburgh Molecular Library Screening Center 靶标：furin (paired basic amino acid cleaving enzyme), isoform CRA_a [Homo sapiens] External Id：MH080376 Biochemical HTS for Inhibitors of the Proprotein Convertase Furin.

实验名称：Fluorescence polarization to screen for inhibitor that competite the binding of FadD2... 来源：Broad Institute 靶标：FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA SYNTHETASE) External Id：2147-01_Inhibitor_SinglePoint_HTS_Activity

实验名称：Primary Screen Inhibitors of CD40 Signaling in BL2 Cells Measured in Cell-Based Syste... 来源：Broad Institute 靶标：N/A External Id：7124-01_Inhibitor_SinglePoint_HTS_Activity

实验名称：Fluorescence-based cell-based primary high throughput screening assay to identify pos... 来源：The Scripps Research Institute Molecular Screening Center 靶标：muscarinic acetylcholine receptor M1 [Homo sapiens] External Id：CHRM1_PAM_FLUO8_1536_1X%ACT PRUN

实验名称：Fluorescence polarization-based biochemical high throughput primary assay to identify... 来源：The Scripps Research Institute Molecular Screening Center 靶标：RecName: Full=Sialate O-acetylesterase; AltName: Full=H-Lse; AltName: Full=Sialic acid-specific 9-O-acetylesterase; Flags: Precursor [Homo sapiens] External Id：SIAE_INH_FP_1536_1X%INH PRUN

共115条，当前第1页，共12页

1

2

3

4

5

英文别名

• N-(2,1,3-Benzothiadiazol-4-ylsulfonyl)glycine
• 4-{[(1-carboxymethyl)amino]sulfonyl}-2,1,3-benzothiadiazol
• MFCD06660512