6-Me-ATP

• 常用名: 6-Me-ATP
• 英文名: 6-Me-ATP
• CAS号: 3130-39-0
• 分子量: 521.21
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₁H₁₈N₅O₁₃P₃
• 熔点: N/A
• 闪点: N/A

6-Me-ATP用途

6-Me-ATP(N6甲基ATP)是一种N6修饰的ATP衍生物。6-Me-ATP对GSK3表现出优异的结合亲和力,作为GSK3β催化的底物肽磷酸化的磷酸基团供体[1]。

6-Me-ATP名称

• 英文名: N6-Methyl-ATP

6-Me-ATP生物活性

• 描述: 6-Me-ATP(N6甲基ATP)是一种N6修饰的ATP衍生物。6-Me-ATP对GSK3表现出优异的结合亲和力,作为GSK3β催化的底物肽磷酸化的磷酸基团供体[1]。
• 相关类别:
  信号通路 >> 干细胞及 Wnt 通路 >> GSK-3
  研究领域 >> 其他
  信号通路 >> PI3K/Akt/mTOR 信号通路 >> GSK-3
• 参考文献:

  [1]. Dong X, et al. Proteome-Wide Characterizations of N6-Methyl-Adenosine Triphosphate- and N6-Furfuryl-Adenosine Triphosphate-Binding Capabilities of Kinases. Anal Chem. 2021 Oct 5;93(39):13251-13259.

6-Me-ATP物理化学性质

• 分子式: C₁₁H₁₈N₅O₁₃P₃
• 分子量: 521.21
• 精确质量: 521.01100
• PSA: 294.57000
• InChIKey: YHGHMWSHJMSCQQ-UHFFFAOYSA-J
• SMILES: CNc1ncnc2c1ncn2C1OC(COP(=O)([O-])OP(=O)([O-])OP(=O)([O-])[O-])C(O)C1O.[Li+].[Li+].[Li+].[Li+]

6-Me-ATP靶点实验

查看更多实验

实验名称：Substrate activity at recombinant full-length chicken CGAS expressed in Escherichia c... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4338394

实验名称：Tested for contraction of guinea pig isolated urinary bladder detrusor muscle by 1 uM... 来源：ChEMBL 靶标：Cavia porcellus External Id：CHEMBL688417

实验名称：Substrate activity at recombinant full-length mouse CGAS expressed in Escherichia col... 来源：ChEMBL 靶标：Cyclic GMP-AMP synthase External Id：CHEMBL4338393

实验名称：Agonist activity at human P2X4R expressing HEK293 cells assessed as reduction in intr... 来源：ChEMBL 靶标：P2X purinoceptor 4 External Id：CHEMBL5126051

实验名称：Agonist activity at human P2X7R expressing HEK293 cells assessed as reduction in intr... 来源：ChEMBL 靶标：P2X purinoceptor 7 External Id：CHEMBL5126052

实验名称：Agonist activity at human P2X7R expressed in HEK293 cells assessed as reduction in YO... 来源：ChEMBL 靶标：P2X purinoceptor 7 External Id：CHEMBL5126053

实验名称：Tested for contraction of guinea pig vas deferens at 37 degree C; Not active 来源：ChEMBL 靶标：Cavia porcellus External Id：CHEMBL688420

实验名称：Agonist activity at human P2X1R expressing CHO cells assessed as reduction in intrace... 来源：ChEMBL 靶标：P2X purinoceptor 1 External Id：CHEMBL5126047

实验名称：Stability assessed as human NTPDase3-mediated compound hydrolysis 来源：ChEMBL 靶标：Ectonucleoside triphosphate diphosphohydrolase 3 External Id：CHEMBL3364111

实验名称：Agonist activity at human P2X2R expressing CHO cells assessed as reduction in intrace... 来源：ChEMBL 靶标：P2X purinoceptor 2 External Id：CHEMBL5126048

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6-Me-ATP英文别名

• N6-methyl-O5'-(tetrahydroxy-[1]triphosphoryl)-adenosine
• N6-Methyladenosin-5'-triphosphat
• Methyl-N6-ATP
• N6-methyl-ATP
• 6-Methylamino-9β-D-ribofuranosyl-purin-5'-triphosphat