COH34 analog 1

• 常用名: COH34 analog 1
• 英文名: COH34 analog 1
• CAS号: 314248-24-3
• 分子量: 325.38
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₈H₁₅NO₃S
• 熔点: N/A
• 闪点: N/A

COH34 analog 1用途

COH34 analog 1,一种代谢产物,是 COH34 氧化类似物。COH34 是一种有效的 poly(ADP-ribose) glycohydrolase (PARG) 抑制剂。

COH34 analog 1名称

• 中文名: N-(2-Hydroxy-naphthalen-1-ylmethylene)-4-methyl-benzenesulfonamide
• 英文名: COH34 analog 1

COH34 analog 1生物活性

• 描述: COH34 analog 1,一种代谢产物,是 COH34 氧化类似物。COH34 是一种有效的 poly(ADP-ribose) glycohydrolase (PARG) 抑制剂。
• 相关类别:
  研究领域 >> 其他
  信号通路 >> 其他 >> 其他
• 参考文献:

  [1]. Chen SH, et al. Targeting dePARylation selectively suppresses DNA repair-defective and PARP inhibitor-resistant malignancies. Sci Adv. 2019 Apr 10;5(4):eaav4340.

COH34 analog 1物理化学性质

• 分子式: C₁₈H₁₅NO₃S
• 分子量: 325.38
• 储存条件: 2-8°C，密封，干燥

COH34 analog 1靶点实验

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实验名称：A screen for small molecule inhibitors of the human deubiquitinating enzyme, UCH37 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School 靶标：ubiquitin C-terminal hydrolase UCH37 [Homo sapiens] External Id：HMS937_MLP

实验名称：A screen for compounds that inhibit growth of Escherichia coli 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School 靶标：N/A External Id：HMS1158_MLP

实验名称：A screen for compounds that are lethal to S. aureus RN4220 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School 靶标：N/A External Id：HMS1364-MLP_WT

实验名称：A screen for compounds that are lethal to S. aureus RN4220 with the processive glycos... 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School 靶标：N/A External Id：HMS1364-MLP_ugtP

实验名称：High throughput screen for small molecule inhibitors of a hypoxia-regulated fluoresce... 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School 靶标：N/A External Id：HMS1149-MLP

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