α-Amylase/α-Glucosidase-IN-1

• 常用名: α-Amylase/α-Glucosidase-IN-1
• 英文名: α-Amylase/α-Glucosidase-IN-1
• CAS号: 329783-03-1
• 分子量: 211.22
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₁H₉N₅
• 熔点: N/A
• 闪点: N/A

用途

α-淀粉酶/α-葡萄糖苷酶-IN-1(化合物33)是一种有效的α-淀粉酶/α-葡萄糖苷酶抑制剂,α-淀粉酶和α-葡萄糖苷酶的IC50s分别为2.01、2.09µM。动力学研究预测α-淀粉酶/α-葡萄糖苷酶-IN-1具有抗高血糖的潜力[1]。

α-Amylase/α-Glucosidase-IN-1名称

• 英文名: α-Amylase/α-Glucosidase-IN-1

α-Amylase/α-Glucosidase-IN-1生物活性

• 描述: α-淀粉酶/α-葡萄糖苷酶-IN-1(化合物33)是一种有效的α-淀粉酶/α-葡萄糖苷酶抑制剂,α-淀粉酶和α-葡萄糖苷酶的IC50s分别为2.01、2.09µM。动力学研究预测α-淀粉酶/α-葡萄糖苷酶-IN-1具有抗高血糖的潜力[1]。
• 相关类别:
  信号通路 >> 其他 >> 其他
  研究领域 >> 代谢疾病
• 靶点实验:

  EC50: 2.01 µM (α-amylase); 2.09 µM (α-glucosidase)[1]

• 参考文献:

  [1]. Yeye EO,et al. Syntheses, in vitro α-amylase and α-glucosidase dual inhibitory activities of 4-amino-1,2,4-triazole derivatives their molecular docking and kinetic studies. Bioorg Med Chem. 2020 Jun 1;28(11):115467.

α-Amylase/α-Glucosidase-IN-1物理化学性质

• 分子式: C₁₁H₉N₅
• 分子量: 211.22

α-Amylase/α-Glucosidase-IN-1靶点实验

查看更多实验

实验名称：Mixed type inhibition of alpha-amylase (unknown origin) assessed as Vmax using varyin... 来源：ChEMBL 靶标：Alpha-amylase 1A External Id：CHEMBL4623357

实验名称：Uncompetitive inhibition of alpha-glucosidase (unknown origin) assessed as Vmax using... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4623359

实验名称：Cell-based high throughput primary assay to identify activators of GPR151 来源：The Scripps Research Institute Molecular Screening Center 靶标：RecName: Full=G-protein coupled receptor 151; AltName: Full=G-protein coupled receptor PGR7; AltName: Full=GPCR-2037; AltName: Full=Galanin receptor 4; AltName: Full=Galanin-receptor-like protein; Short=GalRL External Id：GPR151_PHUNTER_AG_LUMI_1536_1X%ACT

实验名称：AlphaScreen-based biochemical high throughput primary assay to identify activators of... 来源：The Scripps Research Institute Molecular Screening Center 靶标：N/A External Id：FBW7_ACT_ALPHA_1536_1X%ACT PRUN

实验名称：AlphaScreen-based biochemical high throughput primary assay to identify inhibitors of... 来源：The Scripps Research Institute Molecular Screening Center External Id：MITF_INH_Alpha_1536_1X%INH PRUN

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