5-phenyl-N-[4-(pyrrolidin-1-ylmethyl)pyridin-2-yl]-1,3-thiazol-2-amine

• 常用名: 5-phenyl-N-[4-(pyrrolidin-1-ylmethyl)pyridin-2-yl]-1,3-thiazol-2-amine
• 英文名: 5-phenyl-N-[4-(pyrrolidin-1-ylmethyl)pyridin-2-yl]-1,3-thiazol-2-amine
• CAS号: 329793-06-8
• 分子量: 336.5
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₉H₂₀N₄S
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: 5-phenyl-N-[4-(pyrrolidin-1-ylmethyl)pyridin-2-yl]-1,3-thiazol-2-amine

物理化学性质

• 分子式: C₁₉H₂₀N₄S
• 分子量: 336.5
• InChIKey: JBIXJDQVQFSQHB-UHFFFAOYSA-N
• SMILES: C1CCN(C1)CC2=CC(=NC=C2)NC3=NC=C(S3)C4=CC=CC=C4

靶点实验

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实验名称：Metabolic stability in rat liver microsome 来源：ChEMBL 靶标：Liver microsomes External Id：CHEMBL913862

实验名称：Inhibition of VEGF-induced KDR autophosphorylation expressed in HEK293 cells 来源：ChEMBL 靶标：Vascular endothelial growth factor receptor 2 External Id：CHEMBL912804

实验名称：Displacement of [35S]MK4999 from human ERG expressed in HEK293 cells 来源：ChEMBL 靶标：Potassium voltage-gated channel subfamily H member 2 External Id：CHEMBL913858

实验名称：Half life in iv dosed dog 来源：ChEMBL 靶标：Canis lupus familiaris External Id：CHEMBL913859

实验名称：Clearance in iv dosed dog 来源：ChEMBL 靶标：Canis lupus familiaris External Id：CHEMBL913860

实验名称：Inhibition of KDR 来源：ChEMBL 靶标：Vascular endothelial growth factor receptor 2 External Id：CHEMBL913856

实验名称：Inhibition of VEGF-induced DNA synthesis in HEK293 cells expressing human KDR by endo... 来源：ChEMBL 靶标：Vascular endothelial growth factor receptor 2 External Id：CHEMBL913857

实验名称：Kinase Inhibition Assay from Article 10.1021/jm049697f: "Potent N-(1,3-thiazol-2-yl)p... 来源：BindingDB 靶标：N/A External Id：BindingDB_715_1

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