5-Methoxy-2-pyridin-2-yl-4-pyrrolidin-1-ylpyrimidine

• 常用名: 5-Methoxy-2-pyridin-2-yl-4-pyrrolidin-1-ylpyrimidine
• 英文名: 5-Methoxy-2-pyridin-2-yl-4-pyrrolidin-1-ylpyrimidine
• CAS号: 338772-40-0
• 分子量: 256.3
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₄H₁₆N₄O
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: 5-Methoxy-2-pyridin-2-yl-4-pyrrolidin-1-ylpyrimidine

物理化学性质

• 分子式: C₁₄H₁₆N₄O
• 分子量: 256.3
• InChIKey: HDTFWSMQGOILNL-UHFFFAOYSA-N
• SMILES: COC1=CN=C(N=C1N2CCCC2)C3=CC=CC=N3

靶点实验

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实验名称：Inhibition of human hepcidin-stimulated recombinant C-terminal Halo-tagged human FPN ... 来源：ChEMBL 靶标：Hepcidin External Id：CHEMBL4418351

实验名称：NOVARTIS: Inhibition of Plasmodium falciparum 3D7 (drug-susceptible) proliferation in... 来源：ChEMBL 靶标：Plasmodium falciparum External Id：CHEMBL1040691

实验名称：Cmax in ovariectomized Wistar rat at 3 mg/kg, po administered as single dose 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL2073267

实验名称：AUC (0 to infinity) in ovariectomized Wistar rat at 3 mg/kg, po administered as singl... 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL2073268

实验名称：Drug metabolism in human liver microsome assessed as 4-{[5-methoxy-2-(pyridin-2-yl)py... 来源：ChEMBL 靶标：Liver microsomes External Id：CHEMBL2073259

实验名称：AUC (0 to infinity) in male C57BL/6 mouse at 1 mg/kg, po administered as single dose 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL2073265

实验名称：ASTRAZENECA: % bound to plasma by equilibrium dialysis. Compound is incubated with wh... 来源：ChEMBL 靶标：N/A External Id：CHEMBL3301365

实验名称：NOVARTIS: Inhibition Frequency Index (IFI) - the number of HTS assays where a compoun... 来源：ChEMBL 靶标：N/A External Id：CHEMBL1040694

实验名称：NOVARTIS: Inhibition of Plasmodium falciparum W2 (drug-resistant) proliferation in er... 来源：ChEMBL 靶标：Plasmodium falciparum External Id：CHEMBL1040692

实验名称：NOVARTIS: Cytotoxicity against human hepatocellular carcinoma cell line (Huh7) 来源：ChEMBL 靶标：Huh-7 External Id：CHEMBL1040693

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