(R)-1-(2,6-difluorobenzyl)-3-(2-amino-2-phenylethyl)-5-(3-methoxyphenyl)-6-methylpyrimidine-2,4(1H,3H)-dione

• 常用名: (R)-1-(2,6-difluorobenzyl)-3-(2-amino-2-phenylethyl)-5-(3-methoxyphenyl)-6-methylpyrimidine-2,4(1H,3H)-dione
• 英文名: (R)-1-(2,6-difluorobenzyl)-3-(2-amino-2-phenylethyl)-5-(3-methoxyphenyl)-6-methylpyrimidine-2,4(1H,3H)-dione
• CAS号: 352290-62-1
• 分子量: 477.5
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₇H₂₅F₂N₃O₃
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: (R)-1-(2,6-difluorobenzyl)-3-(2-amino-2-phenylethyl)-5-(3-methoxyphenyl)-6-methylpyrimidine-2,4(1H,3H)-dione

物理化学性质

• 分子式: C₂₇H₂₅F₂N₃O₃
• 分子量: 477.5
• InChIKey: SPHKXPKCNHWKFN-DEOSSOPVSA-N
• SMILES: COc1cccc(-c2c(C)n(Cc3c(F)cccc3F)c(=O)n(CC(N)c3ccccc3)c2=O)c1

靶点实验

查看更多实验

实验名称：Inhibition of Human gonadotropin-releasing hormone receptor stimulated calcium flux 来源：ChEMBL 靶标：Gonadotropin-releasing hormone receptor External Id：CHEMBL828596

实验名称：Binding affinity to human GnRHR 来源：ChEMBL 靶标：Gonadotropin-releasing hormone receptor External Id：CHEMBL923765

实验名称：Terminal half-life in monkey after treatment with 10 mg/kg (po. and iv.) 来源：ChEMBL 靶标：N/A External Id：CHEMBL851816

实验名称：Binding affinity for Rat gonadotropin-releasing hormone receptor 来源：ChEMBL 靶标：Gonadotropin-releasing hormone receptor External Id：CHEMBL839508

实验名称：Time taken for plasma concentration reached maximum value in monkey after treatment w... 来源：ChEMBL 靶标：N/A External Id：CHEMBL840672

实验名称：Binding affinity for Monkey gonadotropin-releasing hormone receptor 来源：ChEMBL 靶标：Gonadotropin-releasing hormone receptor External Id：CHEMBL828774

实验名称：Plasma clearance in monkey after treatment with 10 mg/kg (po. and iv.) 来源：ChEMBL 靶标：N/A External Id：CHEMBL839791

实验名称：Binding affinity at human GnRH receptor 来源：ChEMBL 靶标：Gonadotropin-releasing hormone receptor External Id：CHEMBL956658

实验名称：Oral bioavailability in monkey (dose 10 mg/kg p.o. and i.v.) 来源：ChEMBL 靶标：N/A External Id：CHEMBL851009

实验名称：Volume distribution in monkey after treatment with 10 mg/kg (po. and iv.) 来源：ChEMBL 靶标：N/A External Id：CHEMBL852453

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