(R)-1-(4-benzoyl-2-methylpiperazin-1-yl)-2-(1H-pyrrolo[2,3-b]pyridin-3-yl)ethane-1,2-dione

• 常用名: (R)-1-(4-benzoyl-2-methylpiperazin-1-yl)-2-(1H-pyrrolo[2,3-b]pyridin-3-yl)ethane-1,2-dione
• 英文名: (R)-1-(4-benzoyl-2-methylpiperazin-1-yl)-2-(1H-pyrrolo[2,3-b]pyridin-3-yl)ethane-1,2-dione
• CAS号: 357262-60-3
• 分子量: 376.40900
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₁H₂₀N₄O₃
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: (R)-1-(4-benzoyl-2-methylpiperazin-1-yl)-2-(1H-pyrrolo[2,3-b]pyridin-3-yl)ethane-1,2-dione

物理化学性质

• 分子式: C₂₁H₂₀N₄O₃
• 分子量: 376.40900
• 精确质量: 376.15400
• PSA: 86.37000
• LogP: 1.99450
• InChIKey: CCGWWGUXCYXFJW-CQSZACIVSA-N
• SMILES: CC1CN(C(=O)c2ccccc2)CCN1C(=O)C(=O)c1c[nH]c2ncccc12

靶点实验

查看更多实验

实验名称：Cytotoxicity against human HeLa cells expressing CD4, CCR5 after 3 days 来源：ChEMBL 靶标：HeLa External Id：CHEMBL2321074

实验名称：Antiviral activity against HIV1 来源：ChEMBL 靶标：Human immunodeficiency virus 1 External Id：CHEMBL3611391

实验名称：Inhibition of HIV1 JRFL gp120/CD4 interaction in human HeLa67 cells assessed as inhib... 来源：ChEMBL 靶标：N/A External Id：CHEMBL1039956

实验名称：HIV Cellular Data 来源：NIAID 靶标：N/A External Id：HIV Cellular Data

实验名称：Inhibition of recombinant CYP3A4 using 7-benzyloxyresorufin as substrate 来源：ChEMBL 靶标：Cytochrome P450 3A4 External Id：CHEMBL1039963

实验名称：Inhibition of recombinant CYP3A4 using benzyloxy-4-(trifluoromethyl)coumarin as subst... 来源：ChEMBL 靶标：Cytochrome P450 3A4 External Id：CHEMBL1039964

实验名称：Lipophilicity, log D at pH 6.5 来源：ChEMBL 靶标：N/A External Id：CHEMBL1039961

实验名称：Cytotoxicity against human MT2 cells after 3 days by XTT assay 来源：ChEMBL 靶标：MT2 External Id：CHEMBL1039959

实验名称：Antiviral activity against HIV1 pseudovirus in U87 cells expressing CD4 and CCR5 afte... 来源：ChEMBL 靶标：Human immunodeficiency virus 1 External Id：CHEMBL902989

实验名称：Permeability across human Caco-2 cell membrane at pH 6.5 来源：ChEMBL 靶标：Caco-2 External Id：CHEMBL1039960

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英文别名

• 4-benzoyl-2-(R)-methyl-1-[(oxo-1H-pyrrolo[2,3-b]pyridin-3-yl)acetyl]piperazine
• (R)-N-(benzoyl)-3-methyl-N'-[(7-azaindol-3-yl)-oxoacetyl]-piperazine