布瓦西坦

• 常用名: 布瓦西坦
• 英文名: Brivaracetam
• CAS号: 357336-20-0
• 分子量: 212.289
• 密度: 1.1±0.1 g/cm3
• 沸点: 409.3±28.0 °C at 760 mmHg
• 分子式: C₁₁H₂₀N₂O₂
• 熔点: 76.38°
• 闪点: 201.3±24.0 °C

布瓦西坦用途

Brivaracetam(UCB-34714) is a 4-substituted pyrrolidone butanamide as agent with significant antiepileptic activity; high affinity SV2A ligand and also shows an ability to inhibit Na+ channels.

布瓦西坦名称

• 中文名: 布瓦西坦
• 英文名: (2S)-2-[(4R)-2-oxo-4-propylpyrrolidin-1-yl]butanamide
• 中文别名: 布立西坦

布瓦西坦物理化学性质

• 密度: 1.1±0.1 g/cm3
• 沸点: 409.3±28.0 °C at 760 mmHg
• 熔点: 76.38°
• 分子式: C₁₁H₂₀N₂O₂
• 分子量: 212.289
• 闪点: 201.3±24.0 °C
• 精确质量: 212.152481
• PSA: 63.40000
• LogP: 0.88
• InChIKey: MSYKRHVOOPPJKU-BDAKNGLRSA-N
• SMILES: CCCC1CC(=O)N(C(CC)C(N)=O)C1
• 蒸汽压: 0.0±1.0 mmHg at 25°C
• 折射率: 1.494
• 储存条件: -20°C，密闭，干燥

布瓦西坦安全信息

• 海关编码: 2933990090

布瓦西坦海关

• 海关编码: 2933990090
• 中文概述: 2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
• 申报要素: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
• Summary: 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

布瓦西坦靶点实验

查看更多实验

实验名称：Displacement of [3H]-2-[4-(3-azidophenyl)-2-oxo-1-pyrrolidinyl]butanamide from SV2A l... 来源：ChEMBL 靶标：Synaptic vesicle glycoprotein 2A External Id：CHEMBL3880477

实验名称：Anticonvulsant activity in ip dosed sound susceptible DBA mouse model assessed as pro... 来源：ChEMBL 靶标：NON-PROTEIN TARGET External Id：CHEMBL3880478

实验名称：Induction of CYP3A4 in human assessed as reduction in 17alpha-ethinyl estradiol AUC 来源：ChEMBL 靶标：Cytochrome P450 3A4 External Id：CHEMBL5246996

实验名称：Antiviral activity determined as inhibition of SARS-CoV-2 induced cytotoxicity of VER... 来源：ChEMBL 靶标：Severe acute respiratory syndrome coronavirus 2 External Id：CHEMBL4513082

实验名称：Rat synaptic vesicle glycoprotein 2A (Atypical major facilitator superfamily (MSF) pr... 来源：IUPHAR-DB 靶标：synaptic vesicle glycoprotein 2A (Atypical major facilitator superfamily (MSF) proteins) [Rattus norvegicus] External Id：2634_Rat

实验名称：Antiviral activity determined as inhibition of SARS-CoV-2 induced cytotoxicity of Cac... 来源：ChEMBL 靶标：Severe acute respiratory syndrome coronavirus 2 External Id：CHEMBL4303805

实验名称：Cytotoxicity counterscreen for inhibitors of SARS-CoV-2 cell entry 来源：NCGC 靶标：N/A External Id：TRND-SARS-CoV-2-cytotox-48hr

实验名称：In vivo dose required to protect 50% audiogenic seizure prone mice against clonic con... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL716243

实验名称：Half life at 10 mg/kg was determined in rat 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL621316

实验名称：SARS-CoV-2 3CL-Pro protease inhibition percentage at 20µM by FRET kind of response f... 来源：ChEMBL 靶标：Replicase polyprotein 1ab External Id：CHEMBL4495582

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布瓦西坦英文别名

• Briviact
• (2S)-2-[(4R)-2-Oxo-4-propyl-1-pyrrolidinyl]butanamide
• Rikelta
• UCB 34714
• UCB34714
• Brivaracetam