SIBA

• 常用名: SIBA
• 英文名: SIBA
• CAS号: 35899-54-8
• 分子量: 339.41300
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₄H₂₁N₅O₃S
• 熔点: N/A
• 闪点: N/A

SIBA用途

SIBA选择性抑制精胺合成酶, IC50= 8 uM。

SIBA名称

• 中文名: SIBA
• 英文名: 5'-Isobutylthioadenosine

SIBA生物活性

• 描述: SIBA选择性抑制精胺合成酶, IC50= 8 uM。
• 相关类别:
  信号通路 >> 其他 >> 其他
  研究领域 >> 其他
• 参考文献:

  [1]. Carteni-Farina M, et al. Studies on the metabolism of 5'-isobutylthioadenosine (SIBA): phosphorolytic cleavage by methylthioadenosinephosphorylase. FEBS Lett. 1979 Aug 15;104(2):266-270.

  [2]. Lawrence F, et al. Effect of 5'-deoxy-5'-isobutylthioadenosine on putrescine uptake and polyamine biosynthesis by chick embryofibroblasts. Biochem J. 1982 Jun 15;204(3):853-859.

SIBA物理化学性质

• 分子式: C₁₄H₂₁N₅O₃S
• 分子量: 339.41300
• 精确质量: 339.13700
• PSA: 144.61000
• LogP: 0.99810
• InChIKey: JDDUQGRUPLKDNT-IDTAVKCVSA-N
• SMILES: CC(C)CSCC1OC(n2cnc3c(N)ncnc32)C(O)C1O
• 储存条件: 2-8℃

SIBA安全信息

• 海关编码: 2934999090

SIBA海关

• 海关编码: 2934999090
• 中文概述: 2934999090. 其他杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
• 申报要素: 品名, 成分含量, 用途
• Summary: 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

SIBA靶点实验

查看更多实验

实验名称：Inhibition of purified rat liver 5'-nucleotidase using IMP as substrate assessed as r... 来源：ChEMBL 靶标：5'-nucleotidase External Id：CHEMBL4387944

实验名称：Kcat against human methylthioadenosine phosphorylase expressed in Escherichia coli BL... 来源：ChEMBL 靶标：S-methyl-5'-thioadenosine phosphorylase External Id：CHEMBL828699

实验名称：Km against human methylthioadenosine phosphorylase expressed in Escherichia coli BL21... 来源：ChEMBL 靶标：S-methyl-5'-thioadenosine phosphorylase External Id：CHEMBL827246

实验名称：Growth inhibition of Trichomonas vaginalis T1 at 100 uM after 24 hrs by hemocytometry 来源：ChEMBL 靶标：Trichomonas vaginalis External Id：CHEMBL2033839

实验名称：Ratio of Kcat to Km against human Methylthioadenosine phosphorylase 来源：ChEMBL 靶标：S-methyl-5'-thioadenosine phosphorylase External Id：CHEMBL829265

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SIBA英文别名

• 5-isobutylthio-5-deoxyadenosine
• SIBA