喷他佐辛

更新时间:2024-01-05 19:29:58

喷他佐辛结构式
喷他佐辛结构式
委托求购
常用名 喷他佐辛 英文名 (R)-Pentazocine
CAS号 359-83-1 分子量 285.424
密度 1.0±0.1 g/cm3 沸点 403.5±45.0 °C at 760 mmHg
分子式 C19H27NO 熔点 145.4-147.20ºC
MSDS 中文版 美版 闪点 180.8±27.4 °C
符号 GHS07
GHS07
信号词 Warning

 喷他佐辛名称

中文名 喷他佐辛
英文名 6-(2-Fluorophenyl)picolinimidamidehydrochloride
英文别名 更多

 喷他佐辛物理化学性质

密度 1.0±0.1 g/cm3
沸点 403.5±45.0 °C at 760 mmHg
熔点 145.4-147.20ºC
分子式 C19H27NO
分子量 285.424
闪点 180.8±27.4 °C
精确质量 285.209259
PSA 23.47000
LogP 4.53
外观性状 结晶固体
蒸汽压 0.0±1.0 mmHg at 25°C
折射率 1.554
储存条件 Controlled Substance, -20?C Freezer
水溶解性 DMSO: >10mg/mL

 喷他佐辛毒性和生态

 喷他佐辛安全信息

符号 GHS07
GHS07
信号词 Warning
危害声明 H302
警示性声明 P301 + P312 + P330
个人防护装备 dust mask type N95 (US);Eyeshields;Gloves
危害码 (欧洲) Xn: Harmful;
风险声明 (欧洲) R22
安全声明 (欧洲) 7-16-36/37-45
危险品运输编码 UN1230 - class 3 - PG 2 - Methanol, solution
RTECS号 PB8750000

 喷他佐辛合成线路

~94%

喷他佐辛结构式

喷他佐辛

359-83-1

文献:Chen, Qiang; Huo, Xing; Yang, Zhen; She, Xuegong Chemistry - An Asian Journal, 2012 , vol. 7, # 11 p. 2543 - 2546,4

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喷他佐辛结构式

喷他佐辛

359-83-1

文献:Journal of the American Chemical Society, , vol. 125, # 29 p. 8744 - 8745

~%

喷他佐辛结构式

喷他佐辛

359-83-1

文献:Journal of the American Chemical Society, , vol. 125, # 29 p. 8744 - 8745

~%

喷他佐辛结构式

喷他佐辛

359-83-1

文献:Journal of the American Chemical Society, , vol. 125, # 29 p. 8744 - 8745

~%

喷他佐辛结构式

喷他佐辛

359-83-1

文献:Journal of the American Chemical Society, , vol. 125, # 29 p. 8744 - 8745

~%

喷他佐辛结构式

喷他佐辛

359-83-1

文献:Journal of the American Chemical Society, , vol. 125, # 29 p. 8744 - 8745

~%

喷他佐辛结构式

喷他佐辛

359-83-1

文献:Journal of the American Chemical Society, , vol. 125, # 29 p. 8744 - 8745

~%

喷他佐辛结构式

喷他佐辛

359-83-1

文献:Chemistry - An Asian Journal, , vol. 7, # 11 p. 2543 - 2546,4

 喷他佐辛文献78

更多文献
Allosteric modulation of sigma-1 receptors elicits anti-seizure activities.

Br. J. Pharmacol. 172 , 4052-65, (2015)

Application of orthosteric sigma-1 receptor agonists as anti-seizure drugs has been hindered by questionable efficacy and potential adverse effects. Here, we have investigated the anti-seizure effects...

Involvement of hypothalamic neuropeptide Y in pentazocine induced suppression of food intake in rats.

Neuropeptides 48(3) , 133-41, (2014)

The potent orexigenic peptide neuropeptide Y (NPY) has been considered as a possible endogenous ligand for a subpopulation of sigma receptors (SigR). However, their mutual interaction with reference t...

Synthesis and biological evaluation of novel sigma-1 receptor antagonists based on pyrimidine scaffold as agents for treating neuropathic pain.

J. Med. Chem. 57(24) , 10404-23, (2014)

The discovery and synthesis of a new series of pyrimidines as potent sigma-1 receptor (σ1R) antagonists, associated with pharmacological antineuropathic pain activity, are the focus of this article. T...

 喷他佐辛英文别名

Sosigon
UNII:RP4A60D26L
(1R,9R,13R)-1,13-Dimethyl-10-(3-methylbut-2-en-1-yl)-10-azatricyclo[7.3.1.0]trideca-2,4,6-trien-4-ol
Fortalin
α-(−)-Pentazocine
Fortral
Sosegon
(1R,9R,13R)-1,13-diméthyl-10-(3-méthylbut-2-én-1-yl)-10-azatricyclo[7.3.1.0]tridéca-2,4,6-trién-4-ol
2,6-methano-3-benzazocin-8-ol, 1,2,3,4,5,6-hexahydro-6,11-dimethyl-3-(3-methyl-2-butenyl)-, (2R,6R,11R)-
2,6-Methano-3-benzazocin-8-ol, 1,2,3,4,5,6-hexahydro-6,11-dimethyl-3-(3-methyl-2-buten-1-yl)-, (2R,6R,11R)-
II-C-2
cis-(−)-pentazocine
PENTAZOCINE
2-Dimethylallyl-5,9-dimethyl-2'-hydroxybenzomorphan
(2R,6R,11R)-6,11-dimethyl-3-(3-methylbut-2-en-1-yl)-1,2,3,4,5,6-hexahydro-2,6-methano-3-benzazocin-8-ol
Pentagin