3-酮基七鳃鳗醇

• 常用名: 3-酮基七鳃鳗醇
• 英文名: 3-Keto petromyzonol
• CAS号: 359436-56-9
• 分子量: 392.572
• 密度: 1.1±0.1 g/cm3
• 沸点: 543.7±50.0 °C at 760 mmHg
• 分子式: C₂₄H₄₀O₄
• 熔点: 195ºC
• 闪点: 296.7±26.6 °C

3-酮基七鳃鳗醇用途

3-Keto petromyzonol 是雄性七鳃鳗性信息素的主要成分之一,可调节促性腺激素释放激素 (GnRH) 的合成和释放,进而调节未成熟七鳃鳗的下丘脑-垂体-性腺 (HPG) 输出。

3-酮基七鳃鳗醇名称

• 中文名: 3-酮基七鳃鳗醇
• 英文名: 3-keto petromyzonol
• 中文别名: (5A,7A,12A)-7,12,24-三羟基胆烷-3-酮

3-酮基七鳃鳗醇生物活性

• 描述: 3-Keto petromyzonol 是雄性七鳃鳗性信息素的主要成分之一,可调节促性腺激素释放激素 (GnRH) 的合成和释放,进而调节未成熟七鳃鳗的下丘脑-垂体-性腺 (HPG) 输出。
• 相关类别:
  研究领域 >> 内分泌
  信号通路 >> 其他 >> 其他
• 参考文献:

  [1]. Yu-Wen Chung-Davidson, et al. Pheromonal Bile Acid 3-ketopetromyzonol Sulfate Primes the Neuroendocrine System in Sea Lamprey. BMC Neurosci. 2013 Jan 20;14:11.

3-酮基七鳃鳗醇物理化学性质

• 密度: 1.1±0.1 g/cm3
• 沸点: 543.7±50.0 °C at 760 mmHg
• 熔点: 195ºC
• 分子式: C₂₄H₄₀O₄
• 分子量: 392.572
• 闪点: 296.7±26.6 °C
• 精确质量: 392.292664
• PSA: 77.76000
• LogP: 2.30
• InChIKey: WKLORKLFLMTHHY-RTYFXBAISA-N
• SMILES: CC(CCCO)C1CCC2C3C(O)CC4CC(=O)CCC4(C)C3CC(O)C12C
• 蒸汽压: 0.0±3.3 mmHg at 25°C
• 折射率: 1.545

3-酮基七鳃鳗醇靶点实验

查看更多实验

实验名称：Discovery of Small Molecules to Inhibit Human Cytomegalovirus Nuclear Egress 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School 靶标：HCMV UL50 External Id：HMS1262

实验名称：A screen for small molecules that modulate mitochondrial supercomplex formation 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School 靶标：N/A External Id：HMS1482

实验名称：Cell-based high throughput primary assay to identify activators of GPR151 来源：The Scripps Research Institute Molecular Screening Center 靶标：RecName: Full=G-protein coupled receptor 151; AltName: Full=G-protein coupled receptor PGR7; AltName: Full=GPCR-2037; AltName: Full=Galanin receptor 4; AltName: Full=Galanin-receptor-like protein; Short=GalRL External Id：GPR151_PHUNTER_AG_LUMI_1536_1X%ACT

实验名称：AlphaScreen-based biochemical high throughput primary assay to identify inhibitors of... 来源：The Scripps Research Institute Molecular Screening Center External Id：MITF_INH_Alpha_1536_1X%INH PRUN

实验名称：Stabilization of p53 in human papillomavirus-positive cells 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School 靶标：Cellular tumor antigen p53 External Id：HMS1485

实验名称：Discovering small molecule activators of G protein-gated inwardly-rectifying potassiu... 来源：15621 靶标：G protein-activated inward rectifier potassium channel 2 External Id：VANDERBILT_HTS_GIRK2_MPD

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3-酮基七鳃鳗醇英文别名

• (5α,7α,9ξ,12α,20R)-7,12,24-Trihydroxycholan-3-one
• 7ALPHA,12ALPHA,24-TRIHYDROXY-5ALPHA-CHOLANE-3-ONE
• 3-ketopetromyzonol