MPO-IN-28

• 常用名: MPO-IN-28
• 英文名: MPO-IN-28
• CAS号: 37836-90-1
• 分子量: 231.25
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₁H₁₃N₅O
• 熔点: N/A
• 闪点: N/A

MPO-IN-28用途

MPO-IN-28 (Compound 28) 是一种髓过氧化物酶 (MPO) 抑制剂,IC50 为 44 nM。

MPO-IN-28名称

• 中文名: MPO-IN-28
• 英文名: MPO-IN-28

MPO-IN-28生物活性

• 描述: MPO-IN-28 (Compound 28) 是一种髓过氧化物酶 (MPO) 抑制剂,IC50 为 44 nM。
• 相关类别:
  研究领域 >> 心血管疾病
• 参考文献:

  [1]. Soubhye J, et al. Discovery of Novel Potent Reversible and Irreversible Myeloperoxidase Inhibitors Using Virtual Screening Procedure. J Med Chem. 2017 Aug 10;60(15):6563-6586.

MPO-IN-28物理化学性质

• 分子式: C₁₁H₁₃N₅O
• 分子量: 231.25
• InChIKey: ZJBMSSBTCGJZEE-UHFFFAOYSA-N
• SMILES: COc1ccc2c(C)nc(N=C(N)N)nc2c1
• 储存条件: 2-8℃

MPO-IN-28靶点实验

查看更多实验

实验名称：Inhibition of recombinant MPO (unknown origin) assessed as reduction in TMB peroxidat... 来源：ChEMBL 靶标：Myeloperoxidase External Id：CHEMBL4013919

实验名称：Inhibition of recombinant MPO (unknown origin) assessed as reduction in TMB peroxidat... 来源：ChEMBL 靶标：Myeloperoxidase External Id：CHEMBL4013917

实验名称：Inhibition of recombinant MPO (unknown origin) assessed as reduction in TMB peroxidat... 来源：ChEMBL 靶标：Myeloperoxidase External Id：CHEMBL4013918

实验名称：Inhibition of recombinant MPO (unknown origin) assessed as reduction in taurine chlor... 来源：ChEMBL 靶标：Myeloperoxidase External Id：CHEMBL4013915

实验名称：Chemical Probes of Kaposi's Sarcoma Herpes Virus Latent Infection 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School 靶标：ORF 73 [Human herpesvirus 8 type M] External Id：HMS791

实验名称：Irreversible inhibition of recombinant MPO (unknown origin) assessed as reduction in ... 来源：ChEMBL 靶标：Myeloperoxidase External Id：CHEMBL4013927

实验名称：Small-molecule inhibitors of ST2 (IL1RL1) 来源：20881 靶标：interleukin-1 receptor-like 1 isoform [homo sapiens] External Id：ST2_IL33_Inhibitors_Primary_Screening_77700

实验名称：Inhibition of MPO (unknown origin) assessed as apparent bi-molecular rate constant fo... 来源：ChEMBL 靶标：Myeloperoxidase External Id：CHEMBL4013925

实验名称：ASTRAZENECA: Octan-1-ol/water (pH7.4) distribution coefficent measured by a shake fl... 来源：ChEMBL 靶标：N/A External Id：CHEMBL3301363

实验名称：A screen for compounds that inhibit the activity of LtaS in Staphylococcus aureus 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School External Id：HMS979

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