盐酸氯普鲁卡因

• 常用名: 盐酸氯普鲁卡因
• 英文名: Chloroprocaine Hydrochloride
• CAS号: 3858-89-7
• 分子量: 307.216
• 密度: N/A
• 沸点: 402.6ºC at 760 mmHg
• 分子式: C₁₃H₂₀Cl₂N₂O₂
• 熔点: 176ºC
• 闪点: N/A

盐酸氯普鲁卡因用途

Chloroprocaine hydrochloride (2-Chloroprocaine hydrochloride) 是一种酯类麻醉剂。Chloroprocaine 是一种有效的 Na,K-ATPase 活性抑制剂,IC50 为 13 mM。Chloroprocaine hydrochloride 阻断外周神经。

盐酸氯普鲁卡因名称

• 中文名: 盐酸氯普鲁卡因
• 英文名: chloroprocaine hydrochloride
• 中文别名: 4-氨基-2-氯苯甲酸 2-(二乙氨基)乙酯盐酸盐 | 纳塞卡因

盐酸氯普鲁卡因生物活性

• 描述: Chloroprocaine hydrochloride (2-Chloroprocaine hydrochloride) 是一种酯类麻醉剂。Chloroprocaine 是一种有效的 Na,K-ATPase 活性抑制剂,IC50 为 13 mM。Chloroprocaine hydrochloride 阻断外周神经。
• 相关类别:
  研究领域 >> 神经疾病
• 靶点实验:

  IC50: 13 mM (Na,K-ATPase)[1]

• 体内研究: 小鼠静脉注射盐酸氯普鲁卡因的LD50为97mg/kg,皮下注射盐酸氯普鲁卡因的LD50为950mg/kg[1]。
• 参考文献:

  [1]. H Kutchai, et al. Inhibition of the Na,K-ATPase of Canine Renal Medulla by Several Local Anesthetics. Pharmacol Res. 2001 Apr;43(4):399-403.

  [2]. Chloroprocaine HCl Injection.

盐酸氯普鲁卡因物理化学性质

• 沸点: 402.6ºC at 760 mmHg
• 熔点: 176ºC
• 分子式: C₁₃H₂₀Cl₂N₂O₂
• 分子量: 307.216
• 精确质量: 306.090179
• PSA: 41.57000
• LogP: 3.62590
• InChIKey: SZKQYDBPUCZLRX-UHFFFAOYSA-N
• SMILES: CCN(CC)CCOC(=O)c1ccc(N)cc1Cl.Cl
• 外观性状: 白色结晶粉末
• 储存条件: -20℃
• 稳定性: Stable. Incompatible with strong oxidizing agents.

盐酸氯普鲁卡因毒性和生态

盐酸氯普鲁卡因安全信息

• 危险品运输编码: NONH for all modes of transport

盐酸氯普鲁卡因靶点实验

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盐酸氯普鲁卡因英文别名

• NESACAINE-MPF
• 4-amino-2-chlorobenzoate de 2-(diéthylamino)éthyle chlorhydrate
• 2-diethylaminoethyl 4-amino-2-chlorobenzoate hydrochloride
• Benzoic acid, 4-amino-2-chloro-, 2-(diethylamino)ethyl ester, hydrochloride (1:1)
• 2-(Diethylamino)ethyl 4-amino-2-chlorobenzoate hydrochloride (1:1)
• 2-(Diethylamino)ethyl-4-amino-2-chlorbenzolcarboxylathydrochlorid
• 2-Chloro-4-aminobenzoic Acid Diethylaminoethyl Ester Hydrochloride
• 4-Amino-2-chlorobenzoic Acid 2-(Diethylamino)ethyl Ester Monohydrochloride
• CHLOROPROCAINE HCL
• Chloroprocaine Hydrochloride
• 2-(diethylamino)ethyl 4-amino-2-chlorobenzoate,hydrochloride
• UNII-LT7Z1YW11H
• Nesacaine
• Chlorprocainchlorid