N-(4-isopropoxyphenyl)-4-(6-methoxy-7-(3-morpholinopropoxy)quinazolin-4-yl)piperazine-1-carboxamide

• 常用名: N-(4-isopropoxyphenyl)-4-(6-methoxy-7-(3-morpholinopropoxy)quinazolin-4-yl)piperazine-1-carboxamide
• 英文名: N-(4-isopropoxyphenyl)-4-(6-methoxy-7-(3-morpholinopropoxy)quinazolin-4-yl)piperazine-1-carboxamide
• CAS号: 401903-53-5
• 分子量: 564.7
• 密度: N/A
• 沸点: N/A
• 分子式: C₃₀H₄₀N₆O₅
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: N-(4-isopropoxyphenyl)-4-(6-methoxy-7-(3-morpholinopropoxy)quinazolin-4-yl)piperazine-1-carboxamide

物理化学性质

• 分子式: C₃₀H₄₀N₆O₅
• 分子量: 564.7
• InChIKey: QRJUFNKCBDLAKR-UHFFFAOYSA-N
• SMILES: COc1cc2c(N3CCN(C(=O)Nc4ccc(OC(C)C)cc4)CC3)ncnc2cc1OCCCN1CCOCC1

靶点实验

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实验名称：AUCPO in rat after IV (1.5 mg/Kg)/PO (5 mg/kg) dose 来源：ChEMBL 靶标：N/A External Id：CHEMBL637471

实验名称：Half life in vitro in human liver microsomes 来源：ChEMBL 靶标：Homo sapiens External Id：CHEMBL638752

实验名称：Bioavailability in dog (dose 0.5 mg/kg i.v. and 5 mg/kg p.o.) 来源：ChEMBL 靶标：N/A External Id：CHEMBL875642

实验名称：Inhibition of insulin receptor (not determined) 来源：ChEMBL 靶标：Insulin receptor External Id：CHEMBL697197

实验名称：Inhibition of chimeric PDGF receptor with FLT-3 cytoplasmic domain phosphorylation in... 来源：ChEMBL 靶标：Receptor-type tyrosine-protein kinase FLT3 External Id：CHEMBL766072

实验名称：Bioavailability at a dose of 0.5/5 mg/kg in monkey (i.v./p.o.) expressed as % 来源：ChEMBL 靶标：N/A External Id：CHEMBL637863

实验名称：Bioavailability at a dose of 1.5/5 mg/kg in rat (i.v./p.o.) expressed as % 来源：ChEMBL 靶标：N/A External Id：CHEMBL637864

实验名称：T1/2 in human liver microsomes 来源：ChEMBL 靶标：Homo sapiens External Id：CHEMBL640550

实验名称：Inhibition of protein kinase A or C (not determined) 来源：ChEMBL 靶标：N/A External Id：CHEMBL759469

实验名称：Inhibition of wild type Platelet-derived growth factor receptor beta phosphorylation ... 来源：ChEMBL 靶标：Platelet-derived growth factor receptor beta External Id：CHEMBL763440

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