SW-034538

更新时间：2025-09-25 19:27:08

SW-034538结构式	常用名	SW-034538	英文名	SW-034538
	CAS号	412919-82-5	分子量	404.503
	密度	N/A	沸点	N/A
	分子式	C₁₈H₂₀N₄O₃S₂	熔点	N/A
	MSDS	N/A	闪点	N/A

SW-034538用途

SW-034538是一种有效的TAOK2(千和一激酶2；MAP3K17)抑制剂,IC50为300 nM,对45种激酶中的6种(Raf1,GSK3β,JNK1,IRAK4,HGK和CDK2)具有交叉反应性。

英文名	SW-034538

描述	SW-034538是一种有效的TAOK2(千和一激酶2；MAP3K17)抑制剂,IC50为300 nM,对45种激酶中的6种(Raf1,GSK3β,JNK1,IRAK4,HGK和CDK2)具有交叉反应性。
参考文献	References 1. Piala AT, et al. Bioorg Med Chem Lett. 2016 Aug 15;26(16):3923-7. View Related Products by Target MEKK (MAP3K)

分子式	C₁₈H₂₀N₄O₃S₂
分子量	404.503
InChIKey	JFOPCMLQDWPJEY-UHFFFAOYSA-N
SMILES	CCC(=O)Nc1nc(C)c(-c2csc(Nc3cc(OC)ccc3OC)n2)s1

实验名称：Inhibition of human TAO2
来源：ChEMBL
靶标：Serine/threonine-protein kinase TAO2
External Id：CHEMBL4479307

实验名称：Binding affinity to ASK1 (unknown origin) assessed as change in melting temperature a...
来源：ChEMBL
靶标：Mitogen-activated protein kinase kinase kinase 5
External Id：CHEMBL4479299

实验名称：Binding affinity to rat TAOK2 (1 to 320 residues) expressed in Baculovirus/insect cel...
来源：ChEMBL
靶标：Serine/threonine-protein kinase TAO2
External Id：CHEMBL4479300

实验名称：Inhibition of human CDK1
来源：ChEMBL
靶标：Cyclin-dependent kinase 1
External Id：CHEMBL4479301

实验名称：Inhibition of human GSK3beta
来源：ChEMBL
靶标：Glycogen synthase kinase-3 beta
External Id：CHEMBL4479302

实验名称：Inhibition of human HGK
来源：ChEMBL
靶标：Mitogen-activated protein kinase kinase kinase kinase 4
External Id：CHEMBL4479303

实验名称：Cell-based high throughput primary assay to identify activators of GPR151
来源：The Scripps Research Institute Molecular Screening Center
靶标：RecName: Full=G-protein coupled receptor 151; AltName: Full=G-protein coupled receptor PGR7; AltName: Full=GPCR-2037; AltName: Full=Galanin receptor 4; AltName: Full=Galanin-receptor-like protein; Short=GalRL
External Id：GPR151_PHUNTER_AG_LUMI_1536_1X%ACT

实验名称：Inhibition of human IRAK4
来源：ChEMBL
靶标：Interleukin-1 receptor-associated kinase 4
External Id：CHEMBL4479304

实验名称：Inhibition of human JNK1
来源：ChEMBL
靶标：Mitogen-activated protein kinase 8
External Id：CHEMBL4479305

实验名称：Inhibition of human RAF-1
来源：ChEMBL
靶标：RAF proto-oncogene serine/threonine-protein kinase
External Id：CHEMBL4479306

共17条，当前第1页，共2页