N-Ethyl-4-{[5-(methoxycarbamoyl)-2-methylphenyl]amino}-5-methylpy rrolo[2,1-f][1,2,4]triazine-6-carboxamide

• 常用名: N-Ethyl-4-{[5-(methoxycarbamoyl)-2-methylphenyl]amino}-5-methylpy rrolo[2,1-f][1,2,4]triazine-6-carboxamide
• 英文名: N-Ethyl-4-{[5-(methoxycarbamoyl)-2-methylphenyl]amino}-5-methylpy rrolo[2,1-f][1,2,4]triazine-6-carboxamide
• CAS号: 427878-02-2
• 分子量: 382.41600
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₉H₂₂N₆O₃
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: N-Ethyl-4-{[5-(methoxycarbamoyl)-2-methylphenyl]amino}-5-methylpy rrolo[2,1-f][1,2,4]triazine-6-carboxamide

物理化学性质

• 分子式: C₁₉H₂₂N₆O₃
• 分子量: 382.41600
• 精确质量: 382.17500
• PSA: 119.86000
• LogP: 2.70210
• InChIKey: ZZTMFGIGOADCFX-UHFFFAOYSA-N
• SMILES: CCNC(=O)c1cn2ncnc(Nc3cc(C(=O)NOC)ccc3C)c2c1C

靶点实验

查看更多实验

实验名称：Inhibition of p38alpha 来源：ChEMBL 靶标：Mitogen-activated protein kinase 14 External Id：CHEMBL926123

实验名称：Experimentally measured binding affinity data (IC50) for protein-ligand complexes der... 来源：Shanghai Institute of Organic Chemistry 靶标：N/A External Id：PDBbind-IC50 for protein-ligand complexes

实验名称：Selectivity for p38-alpha over Zap70 来源：ChEMBL 靶标：N/A External Id：CHEMBL926212

实验名称：Antiinflammatory effect in Freund's complete adjuvant-induced Lewis rat arthritis mod... 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL1251170

实验名称：Selectivity for p38alpha over IKKbeta2 来源：ChEMBL 靶标：N/A External Id：CHEMBL926213

实验名称：Antiinflammatory activity in BALB/c mouse serum assessed as inhibition of LPS-induced... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL1251169

实验名称：Selectivity for p38-alpha over HER1 来源：ChEMBL 靶标：N/A External Id：CHEMBL926214

实验名称：Antiinflammatory activity in BALB/c mouse serum assessed as inhibition of LPS-induced... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL1251168

实验名称：Selectivity for p38-alpha over HER2 来源：ChEMBL 靶标：N/A External Id：CHEMBL926215

实验名称：Antiinflammatory activity in human PBMC assessed as inhibition of LPS-induced TNFalph... 来源：ChEMBL 靶标：PBMC External Id：CHEMBL1251167

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英文别名

• 3-ethylaminomethyl-pyrrolidine
• N-ethyl-3-pyrrolidinemethanamine
• N-ethyl-3-pyrrolidinmethaneamine
• ethylpyrrolidin-3-ylmethylamine
• 3-Pyrrolidinemethanamine,N-ethyl