Dehydro-ZINC39395747

更新时间：2025-08-27 09:29:20

Dehydro-ZINC39395747结构式	常用名	Dehydro-ZINC39395747	英文名	Dehydro-ZINC39395747
	CAS号	433248-87-4	分子量	291.35
	密度	N/A	沸点	N/A
	分子式	C₁₂H₉N₃O₂S₂	熔点	N/A
	MSDS	N/A	闪点	N/A

Dehydro-ZINC39395747用途

Dehydro-ZINC39395747 是一种 ZINC39395747 的衍生物。ZINC39395747 是一种有效的细胞色素 b5 还原酶 3 (CYB5R3) 抑制剂,IC50 为 9.14 μM,Kd 为1.11 μM。ZINC39395747 可以增加血管细胞中 NO 的生物利用度。

英文名	Dehydro-ZINC39395747

描述	Dehydro-ZINC39395747 是一种 ZINC39395747 的衍生物。ZINC39395747 是一种有效的细胞色素 b5 还原酶 3 (CYB5R3) 抑制剂,IC50 为 9.14 μM,Kd 为1.11 μM。ZINC39395747 可以增加血管细胞中 NO 的生物利用度。
相关类别	研究领域 >> 其他信号通路 >> 其他 >> 其他
参考文献	[1]. Rahaman MM, et al. Structure Guided Chemical Modifications of Propylthiouracil Reveal Novel Small Molecule Inhibitors of Cytochrome b5 Reductase 3 That Increase Nitric Oxide Bioavailability. J Biol Chem. 2015 Jul 3;290(27):16861-72.

分子式	C₁₂H₉N₃O₂S₂
分子量	291.35
InChIKey	ZBZUSIRGXUAECB-UHFFFAOYSA-N
SMILES	O=c1cc(CSc2nc3ccccc3o2)[nH]c(=S)[nH]1
外观性状	固体
储存条件	-20°C

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来源：Center for Chemical Genomics, University of Michigan
External Id：MScreen:TargetID_600

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来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
External Id：HMS1303

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来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
External Id：HMS979

实验名称：Cell-based high throughput primary assay to identify activators of GPR151
来源：The Scripps Research Institute Molecular Screening Center
靶标：RecName: Full=G-protein coupled receptor 151; AltName: Full=G-protein coupled receptor PGR7; AltName: Full=GPCR-2037; AltName: Full=Galanin receptor 4; AltName: Full=Galanin-receptor-like protein; Short=GalRL
External Id：GPR151_PHUNTER_AG_LUMI_1536_1X%ACT

实验名称：AlphaScreen-based biochemical high throughput primary assay to identify activators of...
来源：The Scripps Research Institute Molecular Screening Center
靶标：N/A
External Id：FBW7_ACT_ALPHA_1536_1X%ACT PRUN

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来源：The Scripps Research Institute Molecular Screening Center
External Id：MITF_INH_Alpha_1536_1X%INH PRUN

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来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
靶标：Chain A, Poliovirus Polymerase With Gtp
External Id：HMS750

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