(S)-4-(2-(3-chlorophenyl)-2-hydroxyethylamino)-3-(6-(4-(4-fluorobutanoyl)piperazin-1-yl)-4-methyl-1H-benzo[d]imidazol-2-yl)pyridin-2(1H)-one

• 常用名: (S)-4-(2-(3-chlorophenyl)-2-hydroxyethylamino)-3-(6-(4-(4-fluorobutanoyl)piperazin-1-yl)-4-methyl-1H-benzo[d]imidazol-2-yl)pyridin-2(1H)-one
• 英文名: (S)-4-(2-(3-chlorophenyl)-2-hydroxyethylamino)-3-(6-(4-(4-fluorobutanoyl)piperazin-1-yl)-4-methyl-1H-benzo[d]imidazol-2-yl)pyridin-2(1H)-one
• CAS号: 468741-46-0
• 分子量: 567.1
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₉H₃₂ClFN₆O₃
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: (S)-4-(2-(3-chlorophenyl)-2-hydroxyethylamino)-3-(6-(4-(4-fluorobutanoyl)piperazin-1-yl)-4-methyl-1H-benzo[d]imidazol-2-yl)pyridin-2(1H)-one

物理化学性质

• 分子式: C₂₉H₃₂ClFN₆O₃
• 分子量: 567.1
• InChIKey: KKACLEOGRMSWFM-XMMPIXPASA-N
• SMILES: Cc1cc(N2CCN(C(=O)CCCF)CC2)cc2[nH]c(-c3c(NCC(O)c4cccc(Cl)c4)cc[nH]c3=O)nc12

靶点实验

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实验名称：Solubility in phosphate buffer at pH 6.5 来源：ChEMBL 靶标：N/A External Id：CHEMBL1115503

实验名称：AUC (0 to 4 hrs) in mouse at 20 mg/kg 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL1115502

实验名称：Inhibition of CYP3A4 assessed as dealkylation of 7-benzyloxy-4-trifluoromethylcoumari... 来源：ChEMBL 靶标：Cytochrome P450 3A4 External Id：CHEMBL1115501

实验名称：In vivo antitumor activity against transgenic mouse Sal cells over expressing IGF1R 来源：ChEMBL 靶标：N/A External Id：CHEMBL1115500

实验名称：Inhibition of IGF1R 来源：ChEMBL 靶标：Insulin-like growth factor 1 receptor External Id：CHEMBL1115499

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