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1,3-Dioxolo[4,5-b]acridin-10(5H)-one,4,11-dimethoxy-5-methyl

更新时间:2025-08-25 12:52:21

1,3-Dioxolo[4,5-b]acridin-10(5H)-one,4,11-dimethoxy-5-methyl结构式
1,3-Dioxolo[4,5-b]acridin-10(5H)-one,4,11-dimethoxy-5-methyl结构式
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常用名 1,3-Dioxolo[4,5-b]acridin-10(5H)-one,4,11-dimethoxy-5-methyl 英文名 1,3-Dioxolo[4,5-b]acridin-10(5H)-one,4,11-dimethoxy-5-methyl
CAS号 475-91-2 分子量 313.30500
密度 1.345g/cm3 沸点 530.4ºC at 760 mmHg
分子式 C17H15NO5 熔点 N/A
MSDS N/A 闪点 274.6ºC

 名称

英文名 4,11-dimethoxy-5-methyl-[1,3]dioxolo[4,5-b]acridin-10-one
英文别名 更多

 物理化学性质

密度 1.345g/cm3
沸点 530.4ºC at 760 mmHg
分子式 C17H15NO5
分子量 313.30500
闪点 274.6ºC
精确质量 313.09500
PSA 58.92000
LogP 2.43760
InChIKey TZZNUDMEMFBPQI-UHFFFAOYSA-N
SMILES COc1c2c(c(OC)c3c1c(=O)c1ccccc1n3C)OCO2
蒸汽压 2.48E-11mmHg at 25°C
折射率 1.619

 毒性和生态

 合成线路

~%

1,3-Dioxolo[4,5-b]acridin-10(5H)-one,4,11-dimethoxy-5-methyl结构式

1,3-Dioxolo[4,5...

475-91-2

文献:Cannon et al. Austral. J. scient. Res., 1952 , vol. 5, p. 406,409

 上下游产品

上游产品  1

下游产品  0

 靶点实验

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External Id:OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN
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靶标:disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens]
External Id:ADAM17_INH_QFRET_1536_1X%INH PRUN
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External Id:CHRM1_AG_FLUO8_1536_1X%ACT PRUN
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来源:NCGC
靶标:TDP1 protein [Homo sapiens]
External Id:TDP1100
实验名称:qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in...
来源:NCGC
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External Id:TDP1101
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External Id:2134-01_Inhibitor_SinglePoint_HTS_Activity_Set2
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External Id:CCHFVOTU-PEP-AMC_INH_FLINT_1536_3X%INH CRUN
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来源:Broad Institute
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External Id:2147-01_Inhibitor_SinglePoint_HTS_Activity
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来源:Broad Institute
靶标:N/A
External Id:Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfected HEK293 cells Inhibition - 7011-01_Antagonist_SinglePoint_HTS_Activity
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External Id:AMA1100
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 英文别名

2,3-Methandiyldioxy-1,4-dimethoxy-N-methyl-acridon
melicopidine
Melicopidin
EINECS 207-502-0
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