8-Chloro-4-(4-methylpiperazin-1-yl)benzofuro[3,2-d]pyrimidine

• 常用名: 8-Chloro-4-(4-methylpiperazin-1-yl)benzofuro[3,2-d]pyrimidine
• 英文名: 8-Chloro-4-(4-methylpiperazin-1-yl)benzofuro[3,2-d]pyrimidine
• CAS号: 489402-96-2
• 分子量: 302.76
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₅H₁₅ClN₄O
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: 8-Chloro-4-(4-methylpiperazin-1-yl)benzofuro[3,2-d]pyrimidine

物理化学性质

• 分子式: C₁₅H₁₅ClN₄O
• 分子量: 302.76
• InChIKey: VUWKQWOFKSEXGA-UHFFFAOYSA-N
• SMILES: CN1CCN(CC1)C2=NC=NC3=C2OC4=C3C=C(C=C4)Cl

靶点实验

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实验名称：Metabolic stability in human liver microsomes assessed as half life 来源：ChEMBL 靶标：Liver microsomes External Id：CHEMBL1919840

实验名称：Antagonist activity at recombinant human histamine H4 receptor 来源：ChEMBL 靶标：Histamine H4 receptor External Id：CHEMBL1919839

实验名称：Metabolic stability in rat liver microsomes assessed as half life 来源：ChEMBL 靶标：Liver microsomes External Id：CHEMBL1919841

实验名称：USP8 deubiquitinase inhibition: Primary qHTS 来源：24642 靶标：ubiquitin specific peptidase 8 External Id：USP8 FAST DUB HTS Primary

实验名称：Displacement of [3H]histamine dihydrochloride from human histamine H4 receptor after ... 来源：ChEMBL 靶标：Histamine H4 receptor External Id：CHEMBL1103488

实验名称：USP17 deubiquitinase inhibition: Primary qHTS 来源：24642 靶标：ubiquitin specific peptidase 17 like family member 5 External Id：USP17 FAST DUB HTS Primary

实验名称：USP7 deubiquitinase inhibition: Primary qHTS 来源：24642 靶标：ubiquitin specific peptidase 7 External Id：USP7 FAST DUB HTS Primary

实验名称：Metabolic stability in rat microsomes assessed as drug remaining after 10 mins 来源：ChEMBL 靶标：N/A External Id：CHEMBL1103555

实验名称：Displacement of [3H]histamine from recombinant human histamine H4 receptor 来源：ChEMBL 靶标：Histamine H4 receptor External Id：CHEMBL1919838

实验名称：USP30 deubiquitinase inhibition: Dose-response Confirmation 来源：24642 靶标：ubiquitin specific peptidase 30 External Id：USP30 FAST DUB HTS Confirmation

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