8-巯基喹啉

• 常用名: 8-巯基喹啉
• 英文名: 8-Thioquinoline
• CAS号: 491-33-8
• 分子量: 161.22400
• 密度: 1.246g/cm3
• 沸点: 303.8ºC at 760 mmHg
• 分子式: C₉H₇NS
• 熔点: N/A
• 闪点: 137.5ºC

8-巯基喹啉用途

硫喔星为螯合萃取剂。

8-巯基喹啉名称

• 中文名: 8-巯基喹啉
• 英文名: quinoline-8-thiol
• 中文别名: 喹啉-8-硫醇 | 硫喔星

8-巯基喹啉物理化学性质

• 密度: 1.246g/cm3
• 沸点: 303.8ºC at 760 mmHg
• 分子式: C₉H₇NS
• 分子量: 161.22400
• 闪点: 137.5ºC
• 精确质量: 161.03000
• PSA: 51.69000
• LogP: 2.52350
• InChIKey: MHTSJSRDFXZFHQ-UHFFFAOYSA-N
• SMILES: Sc1cccc2cccnc12
• 蒸汽压: 0.00163mmHg at 25°C
• 折射率: 1.706

8-巯基喹啉安全信息

• 海关编码: 2933499090

8-巯基喹啉制备

以喹啉为原料，经下列步聚制得本品。将275ml工业氯磺酸搅拌冷至10-20℃，滴加75g喹啉，约1-1.5h完。加热至135-145℃回流6h，开始时有大量氯化氢放出。反应毕，冷至室温，将反应物倾入冰块中，用水稀释，析出棕黄色的沉淀，过滤，得喹啉-8-磺酰氯湿品70-80g。取上述喹啉-8-磺酰氯折纯品25g，溶于80ml浓盐酸中，过滤，滤液冷却。再向冷溶液中滴加80g氯化亚锡溶于200ml浓盐酸的溶液，加热即析出黄色结晶。经充分冷却，过滤，用1：1冷盐酸充分洗涤。再将此粗品溶于氢氧化钠溶液中，用1：1盐酸中和至沉淀析出，得纯品红色针状的二水合物。

8-巯基喹啉海关

• 海关编码: 2933499090
• 中文概述: 2933499090. 其他含喹琳或异喹啉环系的化合物〔但未进一步稠合的〕. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
• 申报要素: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
• Summary: 2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

8-巯基喹啉靶点实验

查看更多实验

实验名称：Biochemical Assay from US Patent US10005735: "Inhibitors of RPN11" 来源：BindingDB 靶标：N/A External Id：BindingDB_3463_1

实验名称：Discovery of Small Molecules to Inhibit Human Cytomegalovirus Nuclear Egress 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School 靶标：HCMV UL50 External Id：HMS1262

实验名称：NCI human tumor cell line growth inhibition assay. Data for the MCF7 Non-Small Cell L... 来源：DTP/NCI 靶标：N/A External Id：MCF7_OneDose

实验名称：Antiproliferative activity against human HCT116 cells after 72 hrs by Cell Titer-Glo ... 来源：ChEMBL 靶标：HCT-116 External Id：CHEMBL4049705

实验名称：Inhibition of CSN5 (unknown origin) using SCFskp2-Nedd8OG as substrate after 1 hr by ... 来源：ChEMBL 靶标：COP9 signalosome complex subunit 5 External Id：CHEMBL4049706

实验名称：NCI human tumor cell line growth inhibition assay. Data for the IGROV1 Non-Small Cell... 来源：DTP/NCI 靶标：N/A External Id：IGROV1_OneDose

实验名称：Inhibition of 26S proteasome regulatory subunit RPN11 deubiquitinating activity in hu... 来源：ChEMBL 靶标：26S proteasome non-ATPase regulatory subunit 14 External Id：CHEMBL4049703

实验名称：Inhibition of 26S proteasome regulatory subunit RPN11 deubiquitinating activity in hu... 来源：ChEMBL 靶标：26S proteasome non-ATPase regulatory subunit 14 External Id：CHEMBL4049704

实验名称：A screen for compounds that inhibit the activity of LtaS in Staphylococcus aureus 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School External Id：HMS979

实验名称：Inhibition of BRCC36 (unknown origin) using DiUbK63TAMRA as substrate by fluorescence... 来源：ChEMBL 靶标：Lys-63-specific deubiquitinase BRCC36 External Id：CHEMBL4049715

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8-巯基喹啉英文别名

• 8-(trifluoromethanesulfonyloxy)quinoline
• 8-thioquinoline
• 8-quinolinethiolate
• 8-MQ
• 8-quinolinylSH
• 8-Quinolinethiol
• 8-Mercaptoquinoline
• SQT-8
• 8-mercaptoquinoline dihydrate