KX1-004

• 常用名: KX1-004
• 英文名: KX1-004
• CAS号: 518058-84-9
• 分子量: 284.29
• 密度: 1.4±0.1 g/cm3
• 沸点: 628.2±50.0 °C at 760 mmHg
• 分子式: C₁₆H₁₃FN₂O₂
• 熔点: N/A
• 闪点: 333.7±30.1 °C

KX1-004用途

KX1-004是Src-PTK抑制剂。

KX1-004名称

• 中文名: 5-氟-N-[(3-羟基苯基)甲基]-1H-吲哚-2-甲酰胺
• 英文名: 1H-​Indole-​2-​carboxamide, 5-​fluoro-​N-​[(3-​hydroxyphenyl)​methyl]​

KX1-004生物活性

• 描述: KX1-004是Src-PTK抑制剂。
• 相关类别:
  信号通路 >> 蛋白酪氨酸激酶 >> SRC
  研究领域 >> 其他
• 参考文献:

  [1]. Harris KC, et al. Prevention of noise-induced hearing loss with Src-PTK inhibitors. Hear Res. 2005 Oct;208(1-2):14-25.

  [2]. Bielefeld EC, et al. A comparison of the protective effects of systemic administration of a pro-glutathione drug and a Src-PTK inhibitor against noise-induced hearing loss. Noise Health. 2005 Oct-Dec;7(29):24-30.

KX1-004物理化学性质

• 密度: 1.4±0.1 g/cm3
• 沸点: 628.2±50.0 °C at 760 mmHg
• 分子式: C₁₆H₁₃FN₂O₂
• 分子量: 284.29
• 闪点: 333.7±30.1 °C
• PSA: 78.88000
• LogP: 3.30
• InChIKey: TUIHIKXCMCXXJG-UHFFFAOYSA-N
• SMILES: O=C(NCc1cccc(O)c1)c1cc2cc(F)ccc2[nH]1
• 外观性状: white solid
• 蒸汽压: 0.0±1.9 mmHg at 25°C
• 折射率: 1.689
• 储存条件: -20℃

KX1-004靶点实验

查看更多实验

实验名称：Primary qHTS assay for small molecule inhibitors of Inositol hexaphosphate kinase 1 (... 来源：NCGC External Id：IP6K1-p1

实验名称：Primary Screen for Target Class Profiling of Small Molecule Inhibitors of Methyltrans... 来源：NCGC External Id：MTASE-p

实验名称：Cytochrome P450 family 3 subfamily A member 4 (CYP3A4) small molecule antagonists: lu... 来源：NCGC External Id：CYP3A4437

实验名称：Primary qHTS to identify gynecologic anti-cancer compounds using libraries of approve... 来源：NCGC 靶标：N/A External Id：OBG420

实验名称：Cytochrome P450 family 2 subfamily D member 6 (CYP2D6) small molecule antagonists: lu... 来源：NCGC External Id：CYP2D6395

实验名称：Cytochrome P450 family 2 subfamily C member 9 (CYP2C9) small molecule antagonists: lu... 来源：NCGC External Id：CYP2C9536

实验名称：Primary qHTS for inhibitors of nuclear receptor binding SET domain protein 2 (NSD2) i... 来源：NCGC External Id：NSD2-synergy-p-2C

实验名称：Primary qHTS for inhibitors of nuclear receptor binding SET domain protein 2 (NSD2) i... 来源：NCGC External Id：NSD2-synergy-p-9B

实验名称：Viability qHTS for spleen associated tyrosine kinase inhibitor (SYKi) drug resistant ... 来源：NCGC External Id：s-sky_synergy-MV-411_DR-CTG72-MIPE_NPC_NPACT_Kinase-p1

实验名称：Cytochrome P450 family 3 subfamily A member 7 (CYP3A7) small molecule antagonists: lu... 来源：NCGC External Id：CYP3A7681

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KX1-004英文别名

• 5-Fluoro-N-(3-hydroxybenzyl)-1H-indole-2-carboxamide
• KX1-004