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3-(4-氧代-3,4-二氢-2-喹唑啉)-丙酸

更新时间:2025-12-12 17:29:06

3-(4-氧代-3,4-二氢-2-喹唑啉)-丙酸结构式
3-(4-氧代-3,4-二氢-2-喹唑啉)-丙酸结构式
品牌特惠专场
常用名 3-(4-氧代-3,4-二氢-2-喹唑啉)-丙酸 英文名 3-(4-oxo-1H-quinazolin-2-yl)propanoic acid
CAS号 5368-37-6 分子量 218.20900
密度 1.41g/cm3 沸点 458.2ºC at 760 mmHg
分子式 C11H10N2O3 熔点 N/A
MSDS N/A 闪点 230.9ºC

 3-(4-氧代-3,4-二氢-2-喹唑啉)-丙酸名称

中文名 3-(4-氧代-3,4-二氢-2-喹唑啉)-丙酸
英文名 3-(4-oxo-1H-quinazolin-2-yl)propanoic acid
英文别名 更多

 3-(4-氧代-3,4-二氢-2-喹唑啉)-丙酸物理化学性质

密度 1.41g/cm3
沸点 458.2ºC at 760 mmHg
分子式 C11H10N2O3
分子量 218.20900
闪点 230.9ºC
精确质量 218.06900
PSA 83.05000
LogP 0.94030
InChIKey HYSISEGNFBAVMJ-UHFFFAOYSA-N
SMILES O=C(O)CCc1nc2ccccc2c(=O)[nH]1
折射率 1.659

 3-(4-氧代-3,4-二氢-2-喹唑啉)-丙酸安全信息

海关编码 2933990090

 3-(4-氧代-3,4-二氢-2-喹唑啉)-丙酸合成线路

~82%

3-(4-氧代-3,4-二氢-2-喹唑啉)-丙酸结构式

3-(4-氧代-3,4-二氢-...

5368-37-6

文献:Usifoh Scientia Pharmaceutica, 2000 , vol. 68, # 3 p. 275 - 279

~91%

3-(4-氧代-3,4-二氢-2-喹唑啉)-丙酸结构式

3-(4-氧代-3,4-二氢-...

5368-37-6

文献:AMGEN INC.; BREGMAN, Howard; BUCHANAN, John L.; CHAKKA, Nagasree; DIMAURO, Erin F.; GUNAYDIN, Hakan; GUZMAN PEREZ, Angel; HUA, Zihao; HUANG, Xin Patent: WO2014/36022 A1, 2014 ; Location in patent: Paragraph 0209-0210 ;

~72%

3-(4-氧代-3,4-二氢-2-喹唑啉)-丙酸结构式

3-(4-氧代-3,4-二氢-...

5368-37-6

文献:Essawy, A.; El-Hashash, M. A.; El-Gendy, A. M.; Hamad, M. M. M. Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1982 , vol. 21, # 6 p. 593 - 595

~67%

3-(4-氧代-3,4-二氢-2-喹唑啉)-丙酸结构式

3-(4-氧代-3,4-二氢-...

5368-37-6

文献:Lindgren, Anders E.G.; Karlberg, Tobias; Ekblad, Torun; Spjut, Sara; Thorsell, Ann-Gerd; Andersson, C. David; Nhan, Ton Tong; Hellsten, Victor; Weigelt, Johan; Linusson, Anna; Schueler, Herwig; Elofsson, Mikael Journal of Medicinal Chemistry, 2013 , vol. 56, # 23 p. 9556 - 9568

~%

3-(4-氧代-3,4-二氢-2-喹唑啉)-丙酸结构式

3-(4-氧代-3,4-二氢-...

5368-37-6

文献:Russian Journal of Organic Chemistry, , vol. 42, # 3 p. 382 - 387

~%

3-(4-氧代-3,4-二氢-2-喹唑啉)-丙酸结构式

3-(4-氧代-3,4-二氢-...

5368-37-6

文献:Journal of Medicinal Chemistry, , vol. 56, # 23 p. 9556 - 9568

 3-(4-氧代-3,4-二氢-2-喹唑啉)-丙酸上下游产品

3-(4-氧代-3,4-二氢-2-喹唑啉)-丙酸上游产品  5

3-(4-氧代-3,4-二氢-2-喹唑啉)-丙酸下游产品  1

 3-(4-氧代-3,4-二氢-2-喹唑啉)-丙酸海关

海关编码 2933990090
中文概述 2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素 品名, 成分含量, 用途, 乌洛托品请注明外观, 6-己内酰胺请注明外观, 签约日期
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 3-(4-氧代-3,4-二氢-2-喹唑啉)-丙酸靶点实验

查看更多实验

实验名称:Primary cell-based high-throughput screening assay for identification of compounds th...
来源:Johns Hopkins Ion Channel Center
靶标:regulator of G-protein signaling 4 isoform 2 [Homo sapiens]
External Id:JHICC_RGS_Act_HTS
实验名称:Luminescence-based cell-based primary high throughput screening assay to identify ago...
来源:The Scripps Research Institute Molecular Screening Center
靶标:mu-type opioid receptor isoform MOR-1 [Homo sapiens]
External Id:OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN
实验名称:QFRET-based biochemical primary high throughput screening assay to identify exosite i...
来源:The Scripps Research Institute Molecular Screening Center
靶标:disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens]
External Id:ADAM17_INH_QFRET_1536_1X%INH PRUN
实验名称:Fluorescence-based cell-based primary high throughput screening assay to identify ago...
来源:The Scripps Research Institute Molecular Screening Center
靶标:muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id:CHRM1_AG_FLUO8_1536_1X%ACT PRUN
实验名称:uHTS identification of small molecule activators of the adaptive arm of the Unfolded ...
来源:Burnham Center for Chemical Genomics
靶标:N/A
External Id:BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay
实验名称:A screen for compounds that inhibit the activity of LtaS in Staphylococcus aureus
来源:ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
External Id:HMS979
实验名称:High throughput fluorescence intensity-based biochemical assay to screen for small mo...
来源:University of Pittsburgh Molecular Library Screening Center
靶标:furin (paired basic amino acid cleaving enzyme), isoform CRA_a [Homo sapiens]
External Id:MH080376 Biochemical HTS for Inhibitors of the Proprotein Convertase Furin.
实验名称:Fluorescence polarization to screen for inhibitor that competite the binding of FadD2...
来源:Broad Institute
靶标:FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA SYNTHETASE)
External Id:2147-01_Inhibitor_SinglePoint_HTS_Activity
实验名称:Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfect...
来源:Broad Institute
靶标:N/A
External Id:Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfected HEK293 cells Inhibition - 7011-01_Antagonist_SinglePoint_HTS_Activity
实验名称:Fluorescence-based cell-based primary high throughput screening assay to identify pos...
来源:The Scripps Research Institute Molecular Screening Center
靶标:muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id:CHRM1_PAM_FLUO8_1536_1X%ACT PRUN
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 3-(4-氧代-3,4-二氢-2-喹唑啉)-丙酸英文别名

3,4-dihydro-4-oxoquinazoline-2-propionic acid
3,4-Dihydro-4-oxo-02-quinazolinepropionic Acid
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