3-(4-氧代-3,4-二氢-2-喹唑啉)-丙酸结构式
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常用名 | 3-(4-氧代-3,4-二氢-2-喹唑啉)-丙酸 | 英文名 | 3-(4-oxo-1H-quinazolin-2-yl)propanoic acid |
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| CAS号 | 5368-37-6 | 分子量 | 218.20900 | |
| 密度 | 1.41g/cm3 | 沸点 | 458.2ºC at 760 mmHg | |
| 分子式 | C11H10N2O3 | 熔点 | N/A | |
| MSDS | N/A | 闪点 | 230.9ºC |
| 中文名 | 3-(4-氧代-3,4-二氢-2-喹唑啉)-丙酸 |
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| 英文名 | 3-(4-oxo-1H-quinazolin-2-yl)propanoic acid |
| 英文别名 | 更多 |
| 密度 | 1.41g/cm3 |
|---|---|
| 沸点 | 458.2ºC at 760 mmHg |
| 分子式 | C11H10N2O3 |
| 分子量 | 218.20900 |
| 闪点 | 230.9ºC |
| 精确质量 | 218.06900 |
| PSA | 83.05000 |
| LogP | 0.94030 |
| InChIKey | HYSISEGNFBAVMJ-UHFFFAOYSA-N |
| SMILES | O=C(O)CCc1nc2ccccc2c(=O)[nH]1 |
| 折射率 | 1.659 |
| 海关编码 | 2933990090 |
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~82%
3-(4-氧代-3,4-二氢-... 5368-37-6 |
| 文献:Usifoh Scientia Pharmaceutica, 2000 , vol. 68, # 3 p. 275 - 279 |
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~91%
3-(4-氧代-3,4-二氢-... 5368-37-6 |
| 文献:AMGEN INC.; BREGMAN, Howard; BUCHANAN, John L.; CHAKKA, Nagasree; DIMAURO, Erin F.; GUNAYDIN, Hakan; GUZMAN PEREZ, Angel; HUA, Zihao; HUANG, Xin Patent: WO2014/36022 A1, 2014 ; Location in patent: Paragraph 0209-0210 ; |
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~72%
3-(4-氧代-3,4-二氢-... 5368-37-6 |
| 文献:Essawy, A.; El-Hashash, M. A.; El-Gendy, A. M.; Hamad, M. M. M. Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1982 , vol. 21, # 6 p. 593 - 595 |
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~67%
3-(4-氧代-3,4-二氢-... 5368-37-6 |
| 文献:Lindgren, Anders E.G.; Karlberg, Tobias; Ekblad, Torun; Spjut, Sara; Thorsell, Ann-Gerd; Andersson, C. David; Nhan, Ton Tong; Hellsten, Victor; Weigelt, Johan; Linusson, Anna; Schueler, Herwig; Elofsson, Mikael Journal of Medicinal Chemistry, 2013 , vol. 56, # 23 p. 9556 - 9568 |
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~%
3-(4-氧代-3,4-二氢-... 5368-37-6 |
| 文献:Russian Journal of Organic Chemistry, , vol. 42, # 3 p. 382 - 387 |
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~%
3-(4-氧代-3,4-二氢-... 5368-37-6 |
| 文献:Journal of Medicinal Chemistry, , vol. 56, # 23 p. 9556 - 9568 |
| 3-(4-氧代-3,4-二氢-2-喹唑啉)-丙酸上游产品 5 | |
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| 3-(4-氧代-3,4-二氢-2-喹唑啉)-丙酸下游产品 1 | |
| 海关编码 | 2933990090 |
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| 中文概述 | 2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0% |
| 申报要素 | 品名, 成分含量, 用途, 乌洛托品请注明外观, 6-己内酰胺请注明外观, 签约日期 |
| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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实验名称:Primary cell-based high-throughput screening assay for identification of compounds th...
来源:Johns Hopkins Ion Channel Center
靶标:regulator of G-protein signaling 4 isoform 2 [Homo sapiens]
External Id:JHICC_RGS_Act_HTS
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实验名称:Luminescence-based cell-based primary high throughput screening assay to identify ago...
来源:The Scripps Research Institute Molecular Screening Center
靶标:mu-type opioid receptor isoform MOR-1 [Homo sapiens]
External Id:OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN
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实验名称:QFRET-based biochemical primary high throughput screening assay to identify exosite i...
来源:The Scripps Research Institute Molecular Screening Center
靶标:disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens]
External Id:ADAM17_INH_QFRET_1536_1X%INH PRUN
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实验名称:Fluorescence-based cell-based primary high throughput screening assay to identify ago...
来源:The Scripps Research Institute Molecular Screening Center
靶标:muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id:CHRM1_AG_FLUO8_1536_1X%ACT PRUN
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实验名称:uHTS identification of small molecule activators of the adaptive arm of the Unfolded ...
来源:Burnham Center for Chemical Genomics
靶标:N/A
External Id:BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay
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实验名称:A screen for compounds that inhibit the activity of LtaS in Staphylococcus aureus
来源:ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
External Id:HMS979
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实验名称:High throughput fluorescence intensity-based biochemical assay to screen for small mo...
来源:University of Pittsburgh Molecular Library Screening Center
靶标:furin (paired basic amino acid cleaving enzyme), isoform CRA_a [Homo sapiens]
External Id:MH080376 Biochemical HTS for Inhibitors of the Proprotein Convertase Furin.
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实验名称:Fluorescence polarization to screen for inhibitor that competite the binding of FadD2...
来源:Broad Institute
靶标:FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA SYNTHETASE)
External Id:2147-01_Inhibitor_SinglePoint_HTS_Activity
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实验名称:Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfect...
来源:Broad Institute
靶标:N/A
External Id:Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfected HEK293 cells Inhibition - 7011-01_Antagonist_SinglePoint_HTS_Activity
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实验名称:Fluorescence-based cell-based primary high throughput screening assay to identify pos...
来源:The Scripps Research Institute Molecular Screening Center
靶标:muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id:CHRM1_PAM_FLUO8_1536_1X%ACT PRUN
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| 3,4-dihydro-4-oxoquinazoline-2-propionic acid |
| 3,4-Dihydro-4-oxo-02-quinazolinepropionic Acid |