N-环丙基-4-吡唑并[1,5-b]吡嗪-3-基-2-嘧啶胺

• 常用名: N-环丙基-4-吡唑并[1,5-b]吡嗪-3-基-2-嘧啶胺
• 英文名: N-cyclopropyl-4-pyrazolo[1,5-b]pyridazin-3-ylpyrimidin-2-amine
• CAS号: 551919-54-1
• 分子量: 252.27500
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₃H₁₂N₆
• 熔点: N/A
• 闪点: N/A

名称

• 中文名: N-环丙基-4-吡唑并[1,5-b]吡嗪-3-基-2-嘧啶胺
• 英文名: N-cyclopropyl-4-pyrazolo[1,5-b]pyridazin-3-ylpyrimidin-2-amine

物理化学性质

• 分子式: C₁₃H₁₂N₆
• 分子量: 252.27500
• 精确质量: 252.11200
• PSA: 68.00000
• LogP: 1.83360
• InChIKey: CAGHIASAHLPQMS-UHFFFAOYSA-N
• SMILES: c1cnn2ncc(-c3ccnc(NC4CC4)n3)c2c1

靶点实验

查看更多实验

实验名称：Metabolic stability at mouse liver S9 fraction after 60 mins 来源：ChEMBL 靶标：N/A External Id：CHEMBL1002024

实验名称：Inhibition of human CDK2 by HTRF assay 来源：ChEMBL 靶标：Cyclin-dependent kinase 2 External Id：CHEMBL1002021

实验名称：Inhibition of GSK3-beta by scintillation proximity assay 来源：ChEMBL 靶标：Glycogen synthase kinase-3 beta External Id：CHEMBL1002020

实验名称：Experimentally measured binding affinity data (IC50) for protein-ligand complexes der... 来源：Shanghai Institute of Organic Chemistry 靶标：N/A External Id：PDBbind-IC50 for protein-ligand complexes

实验名称：Inhibition of VEGFR2 by HTRF assay 来源：ChEMBL 靶标：Vascular endothelial growth factor receptor 2 External Id：CHEMBL1002019

实验名称：Inhibition of CDK4 by radioactive glutathione plate-binding assay 来源：ChEMBL 靶标：Cyclin-dependent kinase 4 External Id：CHEMBL1002018

实验名称：Antitrypanosomal activity against Trypanosoma brucei brucei Lister 427 blood stream f... 来源：ChEMBL 靶标：Trypanosoma brucei brucei External Id：CHEMBL4325174

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英文别名

• N-cyclopropyl-4-{pyrazolo[1,5-b]pyridazin-3-yl}pyrimidin-2-amine
• 3ej1
• 2-Pyrimidinamine,N-cyclopropyl-4-pyrazolo[1,5-b]pyridazin-3-yl
• N-cyclopropyl-4-pyrazolo[1,5-b]pyridazin-3-yl-2-pyridinamine