N-Cyclopropyl-N-methyl-4-pyrazolo[1,5-b]pyridazin-3-yl-2-pyrimidinamine

• 常用名: N-Cyclopropyl-N-methyl-4-pyrazolo[1,5-b]pyridazin-3-yl-2-pyrimidinamine
• 英文名: N-Cyclopropyl-N-methyl-4-pyrazolo[1,5-b]pyridazin-3-yl-2-pyrimidinamine
• CAS号: 551919-58-5
• 分子量: 266.30
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₄H₁₄N₆
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: N-Cyclopropyl-N-methyl-4-pyrazolo[1,5-b]pyridazin-3-yl-2-pyrimidinamine

物理化学性质

• 分子式: C₁₄H₁₄N₆
• 分子量: 266.30
• InChIKey: OAIXSJCARVACKE-UHFFFAOYSA-N
• SMILES: CN(c1nccc(-c2cnn3ncccc23)n1)C1CC1

靶点实验

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实验名称：Inhibition of wild-type human full length DYRK1B (M1 to S629 residues) expressed in b... 来源：ChEMBL 靶标：Dual specificity tyrosine-phosphorylation-regulated kinase 1B External Id：CHEMBL4810634

实验名称：Inhibition of wild-type human full length DYRK2 (M1 to S528 residues) expressed in ma... 来源：ChEMBL 靶标：Dual specificity tyrosine-phosphorylation-regulated kinase 2 External Id：CHEMBL4810635

实验名称：Thermodynamic solubility of the compound at pH 6.8 来源：ChEMBL 靶标：N/A External Id：CHEMBL4810632

实验名称：Inhibition of wild-type human partial length DYRK1A (H129 to S509 residues) expressed... 来源：ChEMBL 靶标：Dual specificity tyrosine-phosphorylation-regulated kinase 1A External Id：CHEMBL4810633

实验名称：Inhibition of wild-type human full length CLK3 (M1 to R490 residues) expressed in bac... 来源：ChEMBL 靶标：Dual specificity protein kinase CLK3 External Id：CHEMBL4810638

实验名称：Inhibition of wild-type human full length CDK2 (M1 to L298 residues) expressed in bac... 来源：ChEMBL 靶标：Cyclin-dependent kinase 2 External Id：CHEMBL4810639

实验名称：Inhibition of wild-type human full length CLK1 (M1 to I484 residues) expressed in bac... 来源：ChEMBL 靶标：Dual specificity protein kinase CLK1 External Id：CHEMBL4810636

实验名称：Inhibition of wild-type human partial length CLK2 (D144 to R498 residues) expressed i... 来源：ChEMBL 靶标：Dual specificity protein kinase CLK2 External Id：CHEMBL4810637

实验名称：Displacement of Kinase tracer 236 from biotinylated DYRK1A (unknown origin) expressed... 来源：ChEMBL 靶标：Dual specificity tyrosine-phosphorylation-regulated kinase 1A External Id：CHEMBL4810626

实验名称：Binding affinity to biotinylated DYRK1A (unknown origin) expressed in Escherichia col... 来源：ChEMBL 靶标：Dual specificity tyrosine-phosphorylation-regulated kinase 1A External Id：CHEMBL4810627

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