齿孔酸; 齿孔菌酸

• 常用名: 齿孔酸; 齿孔菌酸
• 英文名: Eburicoic acid
• CAS号: 560-66-7
• 分子量: 470.73
• 密度: 1.05g/cm3
• 沸点: 572.6ºC at 760mmHg
• 分子式: C₃₁H₅₀O₃
• 熔点: N/A
• 闪点: 314.1ºC

齿孔酸; 齿孔菌酸用途

依布尔酸通过抗氧化和抗炎机制保护肝脏免受CCl4诱导的肝损伤[1]。而依布尔酸具有降糖和降血脂作用[2]。

齿孔酸; 齿孔菌酸名称

• 中文名: 齿孔菌酸
• 英文名: Eburicoic acid

齿孔酸; 齿孔菌酸生物活性

• 描述: 依布尔酸通过抗氧化和抗炎机制保护肝脏免受CCl4诱导的肝损伤[1]。而依布尔酸具有降糖和降血脂作用[2]。
• 相关类别:
  研究领域 >> 心血管疾病
  信号通路 >> 其他 >> 其他
• 参考文献:

  [1]. Huang GJ, et al. Hepatoprotective effects of eburicoic acid and dehydroeburicoic acid from Antrodia camphorata in a mouse model of acute hepatic injury. Food Chem. 2013;141(3):3020-3027.

  [2]. Lin CH, et al. Eburicoic Acid, a Triterpenoid Compound from Antrodia camphorata, Displays Antidiabetic and Antihyperlipidemic Effects in Palmitate-Treated C2C12 Myotubes and in High-Fat Diet-Fed Mice. Int J Mol Sci. 2017;18(11):2314. Published 2017 Nov 2.

齿孔酸; 齿孔菌酸物理化学性质

• 密度: 1.05g/cm3
• 沸点: 572.6ºC at 760mmHg
• 分子式: C₃₁H₅₀O₃
• 分子量: 470.73
• 闪点: 314.1ºC
• 精确质量: 470.37600
• PSA: 57.53000
• LogP: 7.78980
• InChIKey: UGMQOYZVOPASJF-OXUZYLMNSA-N
• SMILES: C=C(CCC(C(=O)O)C1CCC2(C)C3=C(CCC12C)C1(C)CCC(O)C(C)(C)C1CC3)C(C)C
• 折射率: 1.54
• 储存条件: 2-8℃

齿孔酸; 齿孔菌酸靶点实验

查看更多实验

实验名称：Induction apoptosis in human HL60 cells assessed as caspase 3 activity after 6 hrs 来源：ChEMBL 靶标：HL-60 External Id：CHEMBL1002858

实验名称：Growth inhibitory activity against human cancer cell line in the NCI's anticancer dru... 来源：ChEMBL 靶标：Panel NCI-60 (60 carcinoma cell lines) External Id：CHEMBL825037

实验名称：Cytotoxicity against human HS68 cells at 25 to 200 uM after 48 hrs by SRB assay 来源：ChEMBL 靶标：Hs68 External Id：CHEMBL3107296

实验名称：Inhibition of TPA-induced Epstein-Barr virus early antigen activation in Raji cells a... 来源：ChEMBL 靶标：Human gammaherpesvirus 4 External Id：CHEMBL904902

实验名称：Cytotoxicity against human HL60 cells 来源：ChEMBL 靶标：HL-60 External Id：CHEMBL2209130

实验名称：Inhibition of TPA-induced Epstein-Barr virus early antigen activation in Raji cells a... 来源：ChEMBL 靶标：Human gammaherpesvirus 4 External Id：CHEMBL904903

实验名称：Induction apoptosis in human HL60 cells assessed as intranucleosomal DNA fragmentatio... 来源：ChEMBL 靶标：HL-60 External Id：CHEMBL1002854

实验名称：Cytotoxicity against human L02 cells incubated for 24 hrs by MTT assay 来源：ChEMBL 靶标：L02 External Id：CHEMBL4344059

实验名称：Cytotoxicity against human SW480 cells incubated for 24 hrs by MTT assay 来源：ChEMBL 靶标：SW480 External Id：CHEMBL4344058

实验名称：Induction apoptosis in human HL60 cells assessed as condensation of chromatin at 10 u... 来源：ChEMBL 靶标：HL-60 External Id：CHEMBL1002851

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齿孔酸; 齿孔菌酸英文别名

• Eburicosaeure
• Eburicoinsaeure