Altertoxin I

• 常用名: Altertoxin I
• 英文名: Altertoxin I
• CAS号: 56258-32-3
• 分子量: 352.33700
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₀H₁₆O₆
• 熔点: N/A
• 闪点: N/A

Altertoxin I用途

Altertoxin I (Dihydroalterperylenol) 是由 Alternaria alternata 产生的一种醌类真菌毒素,具有诱变作用和细胞毒性,能较弱地干扰代谢通讯。

Altertoxin I名称

• 中文名: Altertoxin I
• 英文名: (6aR,6bS,7S)-3,6a,7,10-tetrahydroxy-4,9-dioxo-4,5,6,6a,6b,7,8,9-octahydroperylene

Altertoxin I生物活性

• 描述: Altertoxin I (Dihydroalterperylenol) 是由 Alternaria alternata 产生的一种醌类真菌毒素,具有诱变作用和细胞毒性,能较弱地干扰代谢通讯。
• 相关类别:
  信号通路 >> 其他 >> 其他
  研究领域 >> 代谢疾病
• 参考文献:

  [1]. Jarolim K, et al. Activation of the Nrf2-ARE pathway by the Alternaria alternata mycotoxins altertoxin I and II. Arch Toxicol. 2017 Jan;91(1):203-216.

  [2]. Boutin BK, et al. Effects of purified altertoxins I, II, and III in the metabolic communication V79 system. J Toxicol Environ Health. 1989;26(1):75-81.

  [3]. Stack ME, et al. Mutagenicity of the Alternaria metabolites altertoxins I, II, and III. Appl Environ Microbiol. 1986 Oct;52(4):718-22.

Altertoxin I物理化学性质

• 分子式: C₂₀H₁₆O₆
• 分子量: 352.33700
• 精确质量: 352.09500
• PSA: 115.06000
• LogP: 1.97340
• InChIKey: GJIALGLHOBXNAT-KPOBHBOGSA-N
• SMILES: O=C1CC(O)C2c3c(ccc(O)c31)-c1ccc(O)c3c1C2(O)CCC3=O
• 储存条件: -20°C，密闭，干燥

Altertoxin I靶点实验

查看更多实验

实验名称：Inhibition of human telomerase by TRAP assay 来源：ChEMBL 靶标：Telomerase reverse transcriptase External Id：CHEMBL3391061

实验名称：Antiproliferative activity against human HeLa cells assessed as reduction in cell via... 来源：ChEMBL 靶标：HeLa External Id：CHEMBL4416731

实验名称：Antiproliferative activity against human A549 cells assessed as reduction in cell via... 来源：ChEMBL 靶标：A549 External Id：CHEMBL4416732

实验名称：Antiproliferative activity against human HCT116 cells assessed as reduction in cell v... 来源：ChEMBL 靶标：HCT-116 External Id：CHEMBL4416733

实验名称：HIV Cellular Data 来源：NIAID 靶标：N/A External Id：HIV Cellular Data

实验名称：Inhibition of recombinant VEGFR2 来源：ChEMBL 靶标：Vascular endothelial growth factor receptor 2 External Id：CHEMBL962872

实验名称：Inhibition of recombinant AKT1 来源：ChEMBL 靶标：RAC-alpha serine/threonine-protein kinase External Id：CHEMBL966174

实验名称：Inhibition of recombinant ARK5 来源：ChEMBL 靶标：NUAK family SNF1-like kinase 1 External Id：CHEMBL966175

实验名称：Inhibition of recombinant VEGFR3 来源：ChEMBL 靶标：Vascular endothelial growth factor receptor 3 External Id：CHEMBL962873

实验名称：Inhibition of recombinant IGF1R 来源：ChEMBL 靶标：Insulin-like growth factor 1 receptor External Id：CHEMBL962870

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Altertoxin I英文别名

• altertoxin I
• 3,6a,7,10-tetrahydroxy-4,9-dioxo-4,5,6,6a,6b,7,8,9-octahydroperylene
• ALTERTOXIN I