3α,12β-Dihydroxycholanoic acid

• 常用名: 3α,12β-Dihydroxycholanoic acid
• 英文名: 3α,12β-Dihydroxycholanoic acid
• CAS号: 570-62-7
• 分子量: 392.57200
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₄H₄₀O₄
• 熔点: N/A
• 闪点: N/A

用途

3α,12β-Dihydroxycholanoic acid 是一种胆汁酸,可以从健康人类尿标本分离出。

名称

• 中文名: (R)-4-((3R,5R,8R,9S,10S,12R,13R,14S,17R)-3,12-二羟基-10,13-二甲基十六氢-1H-环戊二烯并[a]菲-17-基)戊酸
• 英文名: deoxycholic acid

生物活性

• 描述: 3α,12β-Dihydroxycholanoic acid 是一种胆汁酸,可以从健康人类尿标本分离出。
• 相关类别:
  研究领域 >> 代谢疾病
• 靶点实验:

  endogenous metabolite[1]

• 参考文献:

  [1]. Yamaga, N.,et al. Analysis of Bile Acids in Urine Specimens from Healthy Humans: Determination of Several Bile Acids with-Hydroxyl and Carbonyl Groups. Journal of Biochemistry, 1996. 119(4), 725–730.

物理化学性质

• 分子式: C₂₄H₄₀O₄
• 分子量: 392.57200
• 精确质量: 392.29300
• PSA: 77.76000
• LogP: 4.47790
• InChIKey: KXGVEGMKQFWNSR-MFSKYVBHSA-N
• SMILES: CC(CCC(=O)O)C1CCC2C3CCC4CC(O)CCC4(C)C3CC(O)C12C
• 储存条件: 室温， 密封， 干燥

靶点实验

查看更多实验

实验名称：Cytotoxicity against human HuH7 cells assessed as cell viability at 500 uM after 24 h... 来源：ChEMBL 靶标：N/A External Id：CHEMBL1251410

实验名称：Cytotoxicity against human HET-1A cells assessed as cell viability after 24 hrs by MT... 来源：ChEMBL 靶标：N/A External Id：CHEMBL1251409

实验名称：TP_TRANSPORTER: uptake of Lagodeoxycholate at a concentration of 1 u M in NTCP-expres... 来源：ChEMBL 靶标：Sodium/bile acid cotransporter External Id：CHEMBL2078449

实验名称：TP_TRANSPORTER: uptake of Lagodeoxycholate at 1 uM in Oatp1-expressing HeLa cells 来源：ChEMBL 靶标：Solute carrier organic anion transporter family member 1A1 External Id：CHEMBL2075552

实验名称：Cytotoxicity against human HET-1A cells assessed as cell viability at 500 uM after 24... 来源：ChEMBL 靶标：N/A External Id：CHEMBL1251411

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英文别名

• Desoxycholsaeure
• Deoxycholsaeure
• 3α,12α-dihydroxy-(5β)-cholan-24-oic acid
• 3α,12α-Dihydroxy-5α-cholansaeure