Salsolinol-1-carboxylic acid

• 常用名: Salsolinol-1-carboxylic acid
• 英文名: Salsolinol-1-carboxylic acid
• CAS号: 57256-34-5
• 分子量: 223.22500
• 密度: 1.396g/cm3
• 沸点: 489.5ºC at 760mmHg
• 分子式: C₁₁H₁₃NO₄
• 熔点: N/A
• 闪点: 249.8ºC

Salsolinol-1-carboxylic acid用途

Salsolinol-1-carboxylic acid 是中枢神经系统内的一种内源性生物碱 (endogenous alkaloid)。

Salsolinol-1-carboxylic acid名称

• 中文名: 去甲猪毛菜碱-1-羧酸
• 英文名: 6,7-dihydroxy-1-methyl-3,4-dihydro-2H-isoquinoline-1-carboxylic acid

Salsolinol-1-carboxylic acid生物活性

• 描述: Salsolinol-1-carboxylic acid 是中枢神经系统内的一种内源性生物碱 (endogenous alkaloid)。
• 相关类别:
  信号通路 >> 其他 >> 其他
  研究领域 >> 神经疾病
• 参考文献:

  [1]. B Sjöquist,et al. Identification and quantification of 1-carboxysalsolinol and salsolinol in biological samples by gas chromatography--mass spectrometry. J Chromatogr. 1985 Sep 13;343(1):1-8.

  [2]. M A Collins, et al. Oxidative decarboxylation of salsolinol-1-carboxylic acid to 1,2-dehydrosalsolinol: evidence for exclusive catalysis by particulate factors in rat kidney. Arch Biochem Biophys. 1988 May 15;263(1):86-95.

Salsolinol-1-carboxylic acid物理化学性质

• 密度: 1.396g/cm3
• 沸点: 489.5ºC at 760mmHg
• 分子式: C₁₁H₁₃NO₄
• 分子量: 223.22500
• 闪点: 249.8ºC
• 精确质量: 223.08400
• PSA: 89.79000
• LogP: 0.87210
• InChIKey: XHGLVMDBZZZXDP-UHFFFAOYSA-N
• SMILES: CC1(C(=O)O)NCCc2cc(O)c(O)cc21
• 折射率: 1.621

Salsolinol-1-carboxylic acid靶点实验

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实验名称：Primary qHTS for small molecule stabilizers of the endoplasmic reticulum resident pro... 来源：NCGC 靶标：N/A External Id：SERCaMPGLuc-p1-antagonist

实验名称：Validation qHTS for agonist of cAMP-regulated guanine nucleotide exchange factor 3 (E... 来源：NCGC External Id：epac1-activator-v

实验名称：Validation qHTS for antagonist of cAMP-regulated guanine nucleotide exchange factor 3... 来源：NCGC External Id：epac1-inhibitor-v

实验名称：Discovery of Small Molecules to Inhibit Human Cytomegalovirus Nuclear Egress 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School 靶标：HCMV UL50 External Id：HMS1262

实验名称：Validation qHTS for agonist of cAMP-regulated guanine nucleotide exchange factor 4 (E... 来源：NCGC External Id：epac2-activator-v2

实验名称：Validation qHTS for antagonist of cAMP-regulated guanine nucleotide exchange factor 4... 来源：NCGC External Id：epac2-inhibitor-v2

实验名称：qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in... 来源：NCGC 靶标：TDP1 protein [Homo sapiens] External Id：TDP1100

实验名称：qHTS for Stage-Specific Inhibitors of Vaccinia Orthopoxvirus: mCherry Reporter Primar... 来源：NCGC 靶标：67.9K protein [Vaccinia virus] External Id：Vaccinia-p2mCherry

实验名称：qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in... 来源：NCGC 靶标：TDP1 protein [Homo sapiens] External Id：TDP1101

实验名称：Rescue cell viability in cybrid cells with a genetic mutation in complex 1 of the mit... 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School 靶标：N/A External Id：HMS1315

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Salsolinol-1-carboxylic acid英文别名

• 6,7-Dihydroxy-1-methyl-1,2,3,4-tetrahydro-isochinolin-1-carbonsaeure
• Sal-1-CA
• 1-Carboxysalsolinol
• Salsolinol-1-carboxylic acid
• 6,7-dihydroxy-1-methyl-1,2,3,4-tetrahydro-isoquinoline-1-carboxylic acid