2,4-Pteridinediamine,6-[[(4-chlorophenyl)amino]methyl]
更新时间：2025-09-28 12:59:37
![2,4-Pteridinediamine,6-[[(4-chlorophenyl)amino]methyl]结构式](https://image.chemsrc.com/caspic/099/57963-46-9.png)
2,4-Pteridinediamine,6-[[(4-chlorophenyl)amino]methyl]结构式
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常用名 | 2,4-Pteridinediamine,6-[[(4-chlorophenyl)amino]methyl] | 英文名 | 2,4-Pteridinediamine,6-[[(4-chlorophenyl)amino]methyl] |
|---|---|---|---|---|
| CAS号 | 57963-46-9 | 分子量 | 301.73400 | |
| 密度 | 1.562g/cm3 | 沸点 | 616.6ºC at 760mmHg | |
| 分子式 | C13H12ClN7 | 熔点 | N/A | |
| MSDS | N/A | 闪点 | 326.7ºC |
| 英文名 | 6-[(4-chloroanilino)methyl]pteridine-2,4-diamine |
|---|
| 密度 | 1.562g/cm3 |
|---|---|
| 沸点 | 616.6ºC at 760mmHg |
| 分子式 | C13H12ClN7 |
| 分子量 | 301.73400 |
| 闪点 | 326.7ºC |
| 精确质量 | 301.08400 |
| PSA | 115.63000 |
| LogP | 3.08510 |
| InChIKey | GQYLDCYVZGDUET-UHFFFAOYSA-N |
| SMILES | Nc1nc(N)c2nc(CNc3ccc(Cl)cc3)cnc2n1 |
| 折射率 | 1.818 |
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~85%
2,4-Pteridinedi... 57963-46-9 |
| 文献：The United States of America as represented by the Department of Health, Education and Welfare Patent: US4077957 A1, 1978 ; |
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~%
2,4-Pteridinedi... 57963-46-9 |
| 文献：Piper, James R.; Johnson, Cheryl A.; Krauth, Charles A.; Carter, Ronald L.; Hosmer, Carla A.; Queener, Sherry F.; Borotz, Susan E.; Pfefferkorn, Elmer R. Journal of Medicinal Chemistry, 1996 , vol. 39, # 6 p. 1271 - 1280 |
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实验名称：Inhibitory activity against rat liver dihydrofolate reductase
来源：ChEMBL
靶标：Dihydrofolate reductase
External Id：CHEMBL665442
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实验名称：Inhibition of Toxoplasma gondii cell growth
来源：ChEMBL
靶标：Toxoplasma gondii
External Id：CHEMBL813899
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实验名称：Inhibitory activity against Pneumocystis carinii dihydrofolate reductase
来源：ChEMBL
靶标：Dihydrofolate reductase
External Id：CHEMBL664188
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实验名称：Ratio of IC50 rat liver DHFR vs IC50 of Toxoplasma gondii DHFR
来源：ChEMBL
靶标：Dihydrofolate reductase; T. gondii vs rat
External Id：CHEMBL848792
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实验名称：Ratio of IC50 rat liver DHFR vs IC50 of Pneumocystis carinii DHFR
来源：ChEMBL
靶标：Dihydrofolate reductase; P. carinii vs rat
External Id：CHEMBL848791
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实验名称：Inhibitory activity against Toxoplasma gondii dihydrofolate reductase
来源：ChEMBL
靶标：Bifunctional dihydrofolate reductase-thymidylate synthase
External Id：CHEMBL665590
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