腊梅碱

• 常用名: 腊梅碱
• 英文名: Calycanthine
• CAS号: 595-05-1
• 分子量: 346.46900
• 密度: 1.29g/cm3
• 沸点: 531.8ºC at 760mmHg
• 分子式: C₂₂H₂₆N₄
• 熔点: 245° (evac tube)
• 闪点: 310.3ºC

腊梅碱用途

Calycanthine 是从 Psychotria 属中分离出的花萼科生物碱,是一种中枢神经系统毒素,可引起抽搐。

腊梅碱名称

• 中文名: 腊梅碱
• 英文名: calycanthine
• 中文别名: 洋臘梅鹼

腊梅碱生物活性

• 描述: Calycanthine 是从 Psychotria 属中分离出的花萼科生物碱,是一种中枢神经系统毒素,可引起抽搐。
• 相关类别:
  信号通路 >> 其他 >> 其他
  研究领域 >> 神经疾病
• 参考文献:

  [1]. Adjibadé Y, et al. Action of calycanthine on nervous transmission in cockroach central nervous system. Planta Med. 1991 Apr;57(2):99-101.

  [2]. Numan RW, et al. Wintersweet (Chimonanthus praecox) toxicity in four goats. N Z Vet J. 2016 May;64(3):179-81.

腊梅碱物理化学性质

• 密度: 1.29g/cm3
• 沸点: 531.8ºC at 760mmHg
• 熔点: 245° (evac tube)
• 分子式: C₂₂H₂₆N₄
• 分子量: 346.46900
• 闪点: 310.3ºC
• 精确质量: 346.21600
• PSA: 30.54000
• LogP: 3.18840
• InChIKey: XSYCDVWYEVUDKQ-GXRSIYKFSA-N
• SMILES: CN1CCC23c4ccccc4NC1C21CCN(C)C3Nc2ccccc21
• 折射率: 1.711
• 储存条件: -20℃

腊梅碱MSDS

腊梅碱MSDS英文版

腊梅碱靶点实验

查看更多实验

实验名称：Luminescence-based cell-based primary high throughput screening assay to identify ago... 来源：The Scripps Research Institute Molecular Screening Center 靶标：mu-type opioid receptor isoform MOR-1 [Homo sapiens] External Id：OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN

实验名称：QFRET-based biochemical primary high throughput screening assay to identify exosite i... 来源：The Scripps Research Institute Molecular Screening Center 靶标：disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens] External Id：ADAM17_INH_QFRET_1536_1X%INH PRUN

实验名称：Fluorescence-based cell-based primary high throughput screening assay to identify ago... 来源：The Scripps Research Institute Molecular Screening Center 靶标：muscarinic acetylcholine receptor M1 [Homo sapiens] External Id：CHRM1_AG_FLUO8_1536_1X%ACT PRUN

实验名称：uHTS identification of small molecule activators of the adaptive arm of the Unfolded ... 来源：Burnham Center for Chemical Genomics 靶标：N/A External Id：BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay

实验名称：Fluorescence polarization to screen for inhibitor that competite the binding of FadD2... 来源：Broad Institute 靶标：FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA SYNTHETASE) External Id：2147-01_Inhibitor_SinglePoint_HTS_Activity

实验名称：Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfect... 来源：Broad Institute 靶标：N/A External Id：Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfected HEK293 cells Inhibition - 7011-01_Antagonist_SinglePoint_HTS_Activity

实验名称：EZH2/PRC2 methyltransferase inhibitors Measured in Biochemical System Using Plate Rea... 来源：Broad Institute 靶标：histone-lysine N-methyltransferase EZH2 isoform a [Homo sapiens] External Id：2125-01_Inhibitor_SinglePoint_HTS_Activity

实验名称：Fluorescence-based cell-based primary high throughput screening assay to identify pos... 来源：The Scripps Research Institute Molecular Screening Center 靶标：muscarinic acetylcholine receptor M1 [Homo sapiens] External Id：CHRM1_PAM_FLUO8_1536_1X%ACT PRUN

实验名称：Fluorescence polarization-based biochemical high throughput primary assay to identify... 来源：The Scripps Research Institute Molecular Screening Center 靶标：RecName: Full=Sialate O-acetylesterase; AltName: Full=H-Lse; AltName: Full=Sialic acid-specific 9-O-acetylesterase; Flags: Precursor [Homo sapiens] External Id：SIAE_INH_FP_1536_1X%INH PRUN

实验名称：Absorbance-based primary biochemical high throughput screening assay to identify acti... 来源：The Scripps Research Institute Molecular Screening Center 靶标：caspase-3 preproprotein [Homo sapiens] External Id：PROCASPASE3_ACT_EPIABS_1536_1X%ACT PRUN

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腊梅碱英文别名

• (1S,3R)-N-Boc-3-aminocyclopentanecarboxylic acid
• (1S,3R)-cyclopentanecarboxylic acid 3-[[(1,1-dimethylethoxy)carbonyl]amino]
• (1S,3R)-3-tert-butoxycarbonylamino-cyclopentanecarboxylic acid
• (+)-(1S,3R)-N-Boc-b-homocycloleucine
• Calycanthin
• (1R,3S)-N-boc-1-Aminocyclopentane-3-carboxylicacid(e.e.)
• (1S,3R)-3-amino-N-tert-butyloxycarbonylcyclopentanecarboxylic acid
• (-)-(1R,3S)-N-BOC-1-AMINOCYCLOPENTANE-3-CARBOXYLIC ACID
• (1S,3R)-(+)-3-(BOC-AMINO)CYCLOPENTANECARBOXYLIC ACID
• CALYCANTHINE
• (+)-(1S,3R)-N-Boc-3-aMinocyclopentanecarboxylic acidacid