4-[[2-[[4-chloro-3-(trifluoromethyl)phenyl]amino]-3H-benzimidazol-5-yl]oxy]-N-methyl-pyridine-2-carboxamide

• 常用名: 4-[[2-[[4-chloro-3-(trifluoromethyl)phenyl]amino]-3H-benzimidazol-5-yl]oxy]-N-methyl-pyridine-2-carboxamide
• 英文名: 4-[[2-[[4-chloro-3-(trifluoromethyl)phenyl]amino]-3H-benzimidazol-5-yl]oxy]-N-methyl-pyridine-2-carboxamide
• CAS号: 611212-56-7
• 分子量: 461.8
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₁H₁₅ClF₃N₅O₂
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: 4-[[2-[[4-chloro-3-(trifluoromethyl)phenyl]amino]-3H-benzimidazol-5-yl]oxy]-N-methyl-pyridine-2-carboxamide

物理化学性质

• 分子式: C₂₁H₁₅ClF₃N₅O₂
• 分子量: 461.8
• InChIKey: ZJLSMLDOCGOURY-UHFFFAOYSA-N
• SMILES: CNC(=O)c1cc(Oc2ccc3nc(Nc4ccc(Cl)c(C(F)(F)F)c4)[nH]c3c2)ccn1

靶点实验

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实验名称：Inhibition of VEGF-stimulated HUVEC cell proliferation after 72 hrs 来源：ChEMBL 靶标：Vascular endothelial growth factor receptor 2 External Id：CHEMBL895900

实验名称：RAF Kinase Inhibition Assay from Article 10.1021/jm801050k: "Design and Synthesis of ... 来源：BindingDB 靶标：N/A External Id：BindingDB_2913_1

实验名称：Inhibition of Erk phosphorylation in human SK-MEL-28 by Western blotting 来源：ChEMBL 靶标：N/A External Id：CHEMBL946285

实验名称：Rescue cell viability in cybrid cells with a genetic mutation in complex 1 of the mit... 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School 靶标：N/A External Id：HMS1315

实验名称：Inhibition of B-RafV600E mutant by ELISA 来源：ChEMBL 靶标：Serine/threonine-protein kinase B-raf External Id：CHEMBL946282

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