4-({2-[(4-bromophenyl)(methyl)amino]-1H-1,3-benzodiazol-5-yl}oxy)-N-methylpyridine-2-carboxamide

• 常用名: 4-({2-[(4-bromophenyl)(methyl)amino]-1H-1,3-benzodiazol-5-yl}oxy)-N-methylpyridine-2-carboxamide
• 英文名: 4-({2-[(4-bromophenyl)(methyl)amino]-1H-1,3-benzodiazol-5-yl}oxy)-N-methylpyridine-2-carboxamide
• CAS号: 611213-70-8
• 分子量: 452.3
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₁H₁₈BrN₅O₂
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: 4-({2-[(4-bromophenyl)(methyl)amino]-1H-1,3-benzodiazol-5-yl}oxy)-N-methylpyridine-2-carboxamide

物理化学性质

• 分子式: C₂₁H₁₈BrN₅O₂
• 分子量: 452.3
• InChIKey: XLZSBGWFJTXBDS-UHFFFAOYSA-N
• SMILES: CNC(=O)c1cc(Oc2ccc3c(c2)nc(Nc2ccc(Br)cc2)n3C)ccn1

靶点实验

查看更多实验

实验名称：Antiproliferative activity against human SK-MEL-28 cells after 3 days by WST-1 assay 来源：ChEMBL 靶标：SK-MEL-28 External Id：CHEMBL946284

实验名称：Inhibition of C-Raf by ELISA 来源：ChEMBL 靶标：RAF proto-oncogene serine/threonine-protein kinase External Id：CHEMBL946283

实验名称：RAF Kinase Inhibition Assay from Article 10.1021/jm801050k: "Design and Synthesis of ... 来源：BindingDB 靶标：N/A External Id：BindingDB_2913_1

实验名称：Inhibition of Erk phosphorylation in human SK-MEL-28 by Western blotting 来源：ChEMBL 靶标：N/A External Id：CHEMBL946285

实验名称：Half life in mouse at 20 mg/kg, po 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL946295

实验名称：Inhibition of B-RafV600E mutant by ELISA 来源：ChEMBL 靶标：Serine/threonine-protein kinase B-raf External Id：CHEMBL946282

实验名称：Volume of distribution in mouse at 20 mg/kg, po 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL946294

实验名称：Clearance in mouse at 20 mg/kg, po 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL946293

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