4-(3-Chloro-2-fluoroanilino)-6-{[1-(methylsulfonyl)piperidin-4-yl]oxy}-7-methoxyquinazoline

• 常用名: 4-(3-Chloro-2-fluoroanilino)-6-{[1-(methylsulfonyl)piperidin-4-yl]oxy}-7-methoxyquinazoline
• 英文名: 4-(3-Chloro-2-fluoroanilino)-6-{[1-(methylsulfonyl)piperidin-4-yl]oxy}-7-methoxyquinazoline
• CAS号: 612500-85-3
• 分子量: 480.9
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₁H₂₂ClFN₄O₄S
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: 4-(3-Chloro-2-fluoroanilino)-6-{[1-(methylsulfonyl)piperidin-4-yl]oxy}-7-methoxyquinazoline

物理化学性质

• 分子式: C₂₁H₂₂ClFN₄O₄S
• 分子量: 480.9
• InChIKey: BDLUIKGKNQFJIO-UHFFFAOYSA-N
• SMILES: COc1cc2ncnc(Nc3cccc(Cl)c3F)c2cc1OC1CCN(S(C)(=O)=O)CC1

靶点实验

查看更多实验

实验名称：Volume of distribution in Wistar rat at 2 mg/kg, iv and 5 mg/kg, po 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL856369

实验名称：AUC in Wistar rat at 5 mg/kg, po normalized to 1 mg/kg 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL856372

实验名称：Inhibition of tumor volume in human LoVo cell xenografted in nude mouse at 50 mg/kg, ... 来源：ChEMBL 靶标：LoVo External Id：CHEMBL856374

实验名称：Bioavailability in Wistar rat at 2 mg/kg, iv and 5 mg/kg, po 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL856367

实验名称：Clearance in Wistar rat at 2 mg/kg, iv and 5 mg/kg, po 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL856368

实验名称：AUC in nude mouse xenografted with human LoVo cell at 50 mg/kg, po, twice daily 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL856943

实验名称：ASTRAZENECA: Octan-1-ol/water (pH7.4) distribution coefficent measured by a shake fl... 来源：ChEMBL 靶标：N/A External Id：CHEMBL3301363

实验名称：Inhibition of tumor volume in human LoVo cell xenografted in nude mouse at 100 mg/kg,... 来源：ChEMBL 靶标：LoVo External Id：CHEMBL856375

实验名称：Inhibition of tumor volume in human LoVo cell xenografted in nude mouse at 50 mg/kg, ... 来源：ChEMBL 靶标：LoVo External Id：CHEMBL856376

实验名称：ASTRAZENECA: Solubility in pH7.4 buffer using solid starting material using the metho... 来源：ChEMBL 靶标：N/A External Id：CHEMBL3301364

共17条，当前第1页，共2页

1

2