3-hydroxy-4-(5-methylfuran-2-carbonyl)-1-(2-morpholinoethyl)-5-(pyridin-2-yl)-1H-pyrrol-2(5H)-one结构式
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常用名 | 3-hydroxy-4-(5-methylfuran-2-carbonyl)-1-(2-morpholinoethyl)-5-(pyridin-2-yl)-1H-pyrrol-2(5H)-one | 英文名 | 3-hydroxy-4-(5-methylfuran-2-carbonyl)-1-(2-morpholinoethyl)-5-(pyridin-2-yl)-1H-pyrrol-2(5H)-one |
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| CAS号 | 618877-74-0 | 分子量 | 397.4 | |
| 密度 | N/A | 沸点 | N/A | |
| 分子式 | C21H23N3O5 | 熔点 | N/A | |
| MSDS | N/A | 闪点 | N/A |
| 英文名 | 3-hydroxy-4-(5-methylfuran-2-carbonyl)-1-(2-morpholinoethyl)-5-(pyridin-2-yl)-1H-pyrrol-2(5H)-one |
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| 分子式 | C21H23N3O5 |
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| 分子量 | 397.4 |
| InChIKey | CLGFKOCLGWPGPL-UHFFFAOYSA-N |
| SMILES | CC1=CC=C(O1)C(=O)C2=C(C(=O)N(C2C3=CC=CC=N3)CCN4CCOCC4)O |
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实验名称:Primary cell-based high-throughput screening assay for identification of compounds th...
来源:Johns Hopkins Ion Channel Center
靶标:regulator of G-protein signaling 4 isoform 2 [Homo sapiens]
External Id:JHICC_RGS_Act_HTS
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实验名称:HTS to identify inhibitors of TNF-alpha Induced Cell Death in Jurkat FADD-/- Cells.
来源:University of Pittsburgh Molecular Library Screening Center
靶标:N/A
External Id:MH081226: Primary HTS for Inhibitors of a Novel Necrotic Cell Death Pathway # Jurkat FADD-/- Model.
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实验名称:uHTS identification of small molecule activators of the adaptive arm of the Unfolded ...
来源:Burnham Center for Chemical Genomics
靶标:N/A
External Id:BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay
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实验名称:uHTS identification of small molecule inhibitors of tim23-1 yeast via a luminescent a...
来源:Burnham Center for Chemical Genomics
靶标:TPA: Essential component of the Translocase of the Inner Mitochondrial membrane (TIM23 complex); involved in protein import into mitochondrial matrix and inner membrane; with Tim17p, contributes to architecture and function of the import channel [Saccharomyces cerevisiae S288c]
External Id:SBCCG-A419-tim23-1-Primary-Antagonist-Assay
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实验名称:High throughput fluorescence intensity-based biochemical assay to screen for small mo...
来源:University of Pittsburgh Molecular Library Screening Center
靶标:furin (paired basic amino acid cleaving enzyme), isoform CRA_a [Homo sapiens]
External Id:MH080376 Biochemical HTS for Inhibitors of the Proprotein Convertase Furin.
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实验名称:Cell-based high throughput primary assay to identify activators of GPR151
来源:The Scripps Research Institute Molecular Screening Center
靶标:RecName: Full=G-protein coupled receptor 151; AltName: Full=G-protein coupled receptor PGR7; AltName: Full=GPCR-2037; AltName: Full=Galanin receptor 4; AltName: Full=Galanin-receptor-like protein; Short=GalRL
External Id:GPR151_PHUNTER_AG_LUMI_1536_1X%ACT
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实验名称:Discovering small molecule activators of G protein-gated inwardly-rectifying potassiu...
来源:15621
靶标:G protein-activated inward rectifier potassium channel 2
External Id:VANDERBILT_HTS_GIRK2_MPD
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实验名称:uHTS identification of small molecule inhibitors of tim10-1 yeast via a luminescent a...
来源:Burnham Center for Chemical Genomics
靶标:TPA: Essential protein of the mitochondrial intermembrane space, forms a complex with Tim9p (TIM10 complex) that delivers hydrophobic proteins to the TIM22 complex for insertion into the inner membrane [Saccharomyces cerevisiae S288c]
External Id:SBCCG-A413-tim10-1-Primary-Antagonist-Assay
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实验名称:96-well format Chlamydomonas reinhardtii Algae Gravitaxis Assay to measure the differ...
来源:University of Pittsburgh Molecular Library Screening Center
靶标:N/A
External Id:MH081217, Chlamydomonas reinhardtii Gravitaxis Assay to Identify Small Molecule Inhibitors of Cilia.
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实验名称:GPR151 activator identification: cell-based high-throughput counter-screen assay
来源:The Scripps Research Institute Molecular Screening Center
靶标:RecName: Full=Glucose-dependent insulinotropic receptor; AltName: Full=G-protein coupled receptor 119
External Id:GPR119_PHUNTER_AG_LUMI_1536_3X%ACT CSRUN1
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