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7-Methyl-diguanosine triphosphate

更新时间:2025-08-25 17:19:41

7-Methyl-diguanosine triphosphate结构式
7-Methyl-diguanosine triphosphate结构式
品牌特惠专场
常用名 7-Methyl-diguanosine triphosphate 英文名 7-methyl-diguanosine triphosphate
CAS号 62828-64-2 分子量 802.432
密度 N/A 沸点 N/A
分子式 C21H29N10O18P3 熔点 N/A
MSDS N/A 闪点 N/A

 7-Methyl-diguanosine triphosphate用途


7-甲基二鸟苷三磷酸(m7Gp3G)是一种可并入mRNA的cap类似物。7-甲基二鸟苷三磷酸参与哺乳动物细胞的翻译和mRNA降解[1]。

 7-Methyl-diguanosine triphosphate名称

英文名 [(2R,3S,4R,5R)-5-(2-amino-7-methyl-6-oxo-3H-purin-9-ium-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl [[[(2R,3S,4R,5R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl] phosphate

 7-Methyl-diguanosine triphosphate生物活性

描述 7-甲基二鸟苷三磷酸(m7Gp3G)是一种可并入mRNA的cap类似物。7-甲基二鸟苷三磷酸参与哺乳动物细胞的翻译和mRNA降解[1]。
相关类别
参考文献

[1]. Ewa Grudzien, et al. Differential inhibition of mRNA degradation pathways by novel cap analogs. J Biol Chem. 2006 Jan 27;281(4):1857-67.

 7-Methyl-diguanosine triphosphate物理化学性质

分子式 C21H29N10O18P3
分子量 802.432
精确质量 802.087402
InChIKey FHHZHGZBHYYWTG-INFSMZHSSA-O
SMILES Cn1c[n+](C2OC(COP(=O)(O)OP(=O)(O)OP(=O)(O)OCC3OC(n4cnc5c(=O)[nH]c(N)nc54)C(O)C3O)C(O)C2O)c2nc(N)[nH]c(=O)c21

 7-Methyl-diguanosine triphosphate靶点实验

查看更多实验

实验名称:Inhibition of recombinant flag-tagged DcpS (unknown origin) decapping activity assess...
来源:ChEMBL
靶标:m7GpppX diphosphatase
External Id:CHEMBL3992422
实验名称:Inhibition of recombinant flag-tagged DcpS (unknown origin) decapping activity assess...
来源:ChEMBL
靶标:m7GpppX diphosphatase
External Id:CHEMBL3992424
实验名称:Inhibition of eIF4E-mediated translation in flexi rabbit reticulocyte lysate using lu...
来源:ChEMBL
靶标:Eukaryotic translation initiation factor 4E
External Id:CHEMBL3608043
实验名称:Inhibition of recombinant flag-tagged DcpS (unknown origin) decapping activity assess...
来源:ChEMBL
靶标:m7GpppX diphosphatase
External Id:CHEMBL3992423
实验名称:Inhibition of eIF4E-mediated translation in flexi rabbit reticulocyte lysate using lu...
来源:ChEMBL
靶标:Eukaryotic translation initiation factor 4E
External Id:CHEMBL3608168
实验名称:Inhibition of eukaryotic initiation factor 4E in micrococcal nuclease-pretreated rabb...
来源:ChEMBL
靶标:Eukaryotic translation initiation factor 4E
External Id:CHEMBL1023605
实验名称:Drug degradation in aqueous buffer at pH 2 after 4.5 hrs by RP HPLC analysis
来源:ChEMBL
靶标:N/A
External Id:CHEMBL2399732
实验名称:Inhibition of recombinant flag-tagged DcpS (unknown origin) decapping activity assess...
来源:ChEMBL
靶标:m7GpppX diphosphatase
External Id:CHEMBL3992399
实验名称:Inhibition of eukaryotic initiation factor 4E in micrococcal nuclease-pretreated rabb...
来源:ChEMBL
靶标:Eukaryotic translation initiation factor 4E
External Id:CHEMBL1023606
实验名称:Binding affinity to mouse eukaryotic initiation factor 4E expressed in Escherichia co...
来源:ChEMBL
靶标:Eukaryotic translation initiation factor 4E
External Id:CHEMBL1023603
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