Malabaricone C

• 常用名: Malabaricone C
• 英文名: Malabaricone C
• CAS号: 63335-25-1
• 分子量: 358.42800
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₁H₂₆O₅
• 熔点: N/A
• 闪点: N/A

Malabaricone C用途

马拉巴利酮C是一种天然的鞘磷脂合成酶(SMS)抑制剂,SMS 1和2的IC50分别为3和1.5μM[1]。

Malabaricone C名称

• 英文名: malabaricone c

Malabaricone C生物活性

• 描述: 马拉巴利酮C是一种天然的鞘磷脂合成酶(SMS)抑制剂,SMS 1和2的IC50分别为3和1.5μM[1]。
• 相关类别:
  信号通路 >> 其他 >> 其他
  研究领域 >> 代谢疾病
• 参考文献:

  [1]. Othman MA, et al. Malabaricone C as Natural Sphingomyelin Synthase Inhibitor against Diet-Induced Obesity and Its Lipid Metabolism in Mice. ACS Med Chem Lett. 2019;10(8):1154-1158. Published 2019 Jul 3.

Malabaricone C物理化学性质

• 分子式: C₂₁H₂₆O₅
• 分子量: 358.42800
• 精确质量: 358.17800
• PSA: 97.99000
• LogP: 4.66510
• InChIKey: HCOZRFYGIFMIEX-UHFFFAOYSA-N
• SMILES: O=C(CCCCCCCCc1ccc(O)c(O)c1)c1c(O)cccc1O

Malabaricone C靶点实验

查看更多实验

实验名称：Inhibition of SMS2 in HFD-induced obese C57BL/6J mouse liver tissue lysate using NBD-... 来源：ChEMBL 靶标：Phosphatidylcholine:ceramide cholinephosphotransferase 2 External Id：CHEMBL4399522

实验名称：Toxicity in HFD-induced obese C57BL/6J mouse model assessed as effect in daily food i... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4399523

实验名称：Antiobesity activity in HFD-induced obese C57BL/6J mouse model assessed as decrease i... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL4399524

实验名称：Lipid lowering activity in human HepG2 cells assessed as change in oleic acid-induced... 来源：ChEMBL 靶标：HepG2 External Id：CHEMBL4399514

实验名称：Antiobesity activity in HFD-induced obese C57BL/6J mouse model assessed as decrease f... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL4399515

实验名称：Antiobesity activity in HFD-induced obese C57BL/6J mouse model assessed as resistance... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL4399516

实验名称：Antiobesity activity in HFD-induced obese C57BL/6J mouse model assessed as improved l... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL4399517

实验名称：Antiobesity activity in HFD-induced obese C57BL/6J mouse model assessed as reduction ... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL4399518

实验名称：Antiobesity activity in HFD-induced obese C57BL/6J mouse model assessed as reduction ... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL4399519

实验名称：Antiobesity activity in HFD-induced obese C57BL/6J mouse model assessed as reduction ... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL4399520

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Malabaricone C英文别名

• 1-(2,6-Dihydroxyphenyl)-9-(3,4-dihydroxyphenyl)-1-nonanone
• malabaricon C