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甘氨熊去氧胆酸

更新时间:2025-08-20 07:06:03

甘氨熊去氧胆酸结构式
甘氨熊去氧胆酸结构式
品牌特惠专场
常用名 甘氨熊去氧胆酸 英文名 Glycoursodeoxycholic acid
CAS号 64480-66-6 分子量 449.62300
密度 N/A 沸点 N/A
分子式 C26H43NO5 熔点 232-235ºC
MSDS 中文版 美版 闪点 N/A

 甘氨熊去氧胆酸名称

中文名 甘氨熊去氧胆酸
英文名 Glycoursodeoxycholic acid
中文别名 甘氨熊脱氧胆酸
英文别名 更多

 甘氨熊去氧胆酸生物活性

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相关类别

 甘氨熊去氧胆酸物理化学性质

熔点 232-235ºC
分子式 C26H43NO5
分子量 449.62300
精确质量 449.31400
PSA 106.86000
LogP 3.98500
InChIKey GHCZAUBVMUEKKP-XROMFQGDSA-N
SMILES CC(CCC(=O)NCC(=O)O)C1CCC2C3C(O)CC4CC(O)CCC4(C)C3CCC12C
外观性状 固体;White to Almost white powder to crystal
储存条件 -20°C Freezer

 甘氨熊去氧胆酸安全信息

危险品运输编码 NONH for all modes of transport

 甘氨熊去氧胆酸文献38

更多文献
Ultra high resolution SFC-MS as a high throughput platform for metabolic phenotyping: application to metabolic profiling of rat and dog bile.

J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 966 , 200-7, (2014)

Ultra high resolution SFC-MS (on sub-2μm particles) coupled to mass spectrometry has been evaluated for the metabolic profiling of rat and dog bile. The selectivity of the SFC separation differed from...

A possible role of chenodeoxycholic acid and glycine-conjugated bile acids in fibrotic steatohepatitis in a dietary rat model.

Dig. Dis. Sci. 59(7) , 1490-501, (2014)

Our previous study indicated that hepatic bile acids (BAs) may have deposited and stimulated the pathogenesis of a high fat-cholesterol (HFC) diet-induced fibrotic steatohepatitis in stroke-prone spon...

A liquid chromatography-tandem mass spectrometry-based method for the simultaneous determination of hydroxy sterols and bile acids.

J. Chromatogr. A. 1371 , 184-95, (2014)

Recently, hydroxy sterols and bile acids have gained growing interest as they are important regulators of energy homoeostasis and inflammation. The high number of different hydroxy sterols and bile ac...

 甘氨熊去氧胆酸靶点实验

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实验名称:Cytotoxicity against human HuH7 cells assessed as cell viability at 500 uM after 24 h...
来源:ChEMBL
靶标:N/A
External Id:CHEMBL1251410
实验名称:Cytotoxicity against human HET-1A cells assessed as cell viability after 24 hrs by MT...
来源:ChEMBL
靶标:N/A
External Id:CHEMBL1251409
实验名称:TP_TRANSPORTER: transepithelial transport (basal to apical) in Ntcp/Bsep double trans...
来源:ChEMBL
靶标:N/A
External Id:CHEMBL2076062
实验名称:Antagonist activity at FXR (unknown origin) expressed in HEK293T cells cotransfected ...
来源:ChEMBL
靶标:Bile acid receptor
External Id:CHEMBL5098971
实验名称:Cytotoxicity against HEK293T cells cotransfected with pCMV-Script-hFXR/pGL4.11-hSHP-L...
来源:ChEMBL
靶标:HEK-293T
External Id:CHEMBL5098972
实验名称:Anti-NASH activity in GAN diet-induced C57/BL67 mouse assessed as decrease in hydroxy...
来源:ChEMBL
靶标:Mus musculus
External Id:CHEMBL5099029
实验名称:TP_TRANSPORTER: uptake in ASBT-expressing COS cells
来源:ChEMBL
靶标:Ileal sodium/bile acid cotransporter
External Id:CHEMBL2076059
实验名称:Cytotoxicity against human HET-1A cells assessed as cell viability at 500 uM after 24...
来源:ChEMBL
靶标:N/A
External Id:CHEMBL1251411
实验名称:Anti-NASH activity in GAN-induced C57/BL67 mouse assessed as increase in insulin sens...
来源:ChEMBL
靶标:Mus musculus
External Id:CHEMBL5099019
实验名称:Anti-NASH activity in GAN diet-induced C57/BL67 mouse assessed as bile acid level in ...
来源:ChEMBL
靶标:Mus musculus
External Id:CHEMBL5099083
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 甘氨熊去氧胆酸英文别名

Glycoursodeoxycholic Acid
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